Chlorine in PDB 249l: The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect

All present enzymatic activity of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect:
3.2.1.17;

The structure of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect, PDB code: 249l was solved by J.Xu, W.A.Baase, E.Baldwin, B.W.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.90
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	60.870, 60.870, 96.900, 90.00, 90.00, 120.00
R / Rfree (%)	15 / n/a

The binding sites of Chlorine atom in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect (pdb code 249l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect, PDB code: 249l:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl173 b:40.3 occ:1.00 O A:HOH209 3.0 34.5 1.0 N A:ARG145 3.1 12.5 1.0 N A:ASN144 3.3 8.4 1.0 C A:THR142 3.5 19.2 1.0 CA A:THR142 3.5 8.0 1.0 CB A:THR142 3.6 17.1 1.0 CB A:ASN144 3.7 11.2 1.0 O A:THR142 3.7 15.5 1.0 CB A:ARG145 3.7 13.6 1.0 CA A:ASN144 3.8 15.1 1.0 N A:PRO143 3.9 17.9 1.0 C A:ASN144 3.9 20.2 1.0 CA A:ARG145 4.0 13.3 1.0 C A:PRO143 4.2 15.2 1.0 O A:HOH338 4.2 46.7 1.0 CG2 A:THR142 4.3 18.1 1.0 CD A:PRO143 4.3 19.1 1.0 CG A:ASN144 4.6 26.4 1.0 CA A:PRO143 4.6 14.0 1.0 O A:HOH230 4.8 35.8 1.0 OG1 A:THR142 4.8 14.9 1.0 ND2 A:ASN144 4.9 32.5 1.0 O A:HOH237 5.0 38.8 1.0 N A:THR142 5.0 13.7 1.0

Chlorine binding site 2 out of 2 in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl178 b:35.0 occ:0.50 O A:HOH215 3.1 20.2 1.0 O A:HOH182 3.2 25.8 1.0 O A:HOH200 3.5 37.8 1.0 CE1 A:HIS31 3.9 15.5 1.0 O A:HOH246 3.9 63.5 1.0 CB A:ALA49 3.9 16.8 1.0 NE2 A:HIS31 4.0 14.1 1.0 CA A:ALA49 4.3 22.1 1.0 O A:HOH202 4.4 59.3 1.0 NE2 A:GLN69 4.4 15.1 1.0 O A:HOH282 4.5 37.5 1.0 CD2 A:LEU66 4.7 16.3 1.0 O A:ALA49 5.0 15.1 1.0

J.Xu, W.A.Baase, E.Baldwin, B.W.Matthews. The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect. Protein Sci. V. 7 158 1998.
ISSN: ISSN 0961-8368
PubMed: 9514271