Chlorine in PDB 254l: Lysozyme

All present enzymatic activity of Lysozyme:
3.2.1.17;

The structure of Lysozyme, PDB code: 254l was solved by R.Kuroki, B.Shoichet, L.H.Weaver, B.W.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.90
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	61.000, 61.000, 97.200, 90.00, 90.00, 120.00
R / Rfree (%)	15.8 / n/a

The binding sites of Chlorine atom in the Lysozyme (pdb code 254l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Lysozyme, PDB code: 254l:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Lysozyme


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Lysozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl173 b:1.0 occ:1.00 O A:HOH209 2.8 29.8 1.0 N A:ARG145 3.3 10.9 1.0 N A:ASN144 3.4 5.9 1.0 C A:THR142 3.5 18.7 1.0 CA A:THR142 3.6 8.2 1.0 CB A:THR142 3.6 12.9 1.0 CB A:ASN144 3.7 7.7 1.0 O A:THR142 3.9 11.8 1.0 CA A:ASN144 3.9 9.4 1.0 N A:PRO143 3.9 12.7 1.0 CB A:ARG145 3.9 8.5 1.0 C A:ASN144 4.1 13.7 1.0 CA A:ARG145 4.2 9.0 1.0 CG2 A:THR142 4.2 14.2 1.0 CD A:PRO143 4.2 15.7 1.0 C A:PRO143 4.3 12.8 1.0 CG A:ASN144 4.6 25.9 1.0 CA A:PRO143 4.6 15.6 1.0 OG1 A:THR142 4.8 15.6 1.0 O A:HOH230 4.8 31.9 1.0 ND2 A:ASN144 4.8 21.2 1.0 N A:THR142 5.0 10.9 1.0

Chlorine binding site 2 out of 2 in the Lysozyme


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Lysozyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl178 b:3.5 occ:0.50 O A:HOH215 2.8 13.8 1.0 O A:HOH182 3.2 17.6 1.0 O A:HOH200 3.4 26.1 1.0 O A:HOH246 4.0 58.9 1.0 CB A:ALA49 4.1 13.7 1.0 CE1 A:HIS31 4.1 13.6 1.0 NE2 A:GLN69 4.2 14.8 1.0 NE2 A:HIS31 4.3 13.4 1.0 CA A:ALA49 4.5 17.9 1.0 O A:HOH282 4.5 38.0 1.0 CD2 A:LEU66 4.7 14.1 1.0

B.K.Shoichet, W.A.Baase, R.Kuroki, B.W.Matthews. A Relationship Between Protein Stability and Protein Function. Proc.Natl.Acad.Sci.Usa V. 92 452 1995.
ISSN: ISSN 0027-8424
PubMed: 7831309
DOI: 10.1073/PNAS.92.2.452