Chlorine in PDB 2a2c: X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate

The structure of X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate, PDB code: 2a2c was solved by J.B.Thoden, H.M.Holden, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.65
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	123.800, 123.800, 60.100, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The structure of X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Sodium	(Na)	1 atom

The binding sites of Chlorine atom in the X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate (pdb code 2a2c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate, PDB code: 2a2c:

Chlorine binding site 1 out of 1 in the X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of Human N-Acetyl Galactosamine Kinase Complexed with Mg-Adp and N-Acetyl Galactosamine 1-Phosphate within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl461 b:26.9 occ:1.00 O A:HOH644 3.0 34.4 1.0 O A:HOH653 3.1 26.9 1.0 N A:TRP107 3.2 17.5 1.0 CD1 A:TRP107 3.6 20.1 1.0 O A:HOH646 3.6 46.0 1.0 O A:HOH647 3.6 41.2 1.0 CB A:TRP107 3.8 15.2 1.0 CA A:LEU106 4.0 23.2 1.0 C A:LEU106 4.1 20.9 1.0 CG A:TRP107 4.1 16.5 1.0 CA A:TRP107 4.1 16.1 1.0 CD2 A:TYR88 4.4 16.5 1.0 CD2 A:LEU106 4.4 31.7 1.0 CD A:PRO89 4.4 22.7 1.0 CB A:LEU106 4.5 27.8 1.0 O A:HOH805 4.6 71.9 1.0 O A:HOH782 4.6 54.1 1.0 NE1 A:TRP107 4.8 19.9 1.0 O A:LEU87 4.8 18.2 1.0 O A:HOH509 4.9 37.6 1.0 CE2 A:TYR88 5.0 15.7 1.0 O A:PRO105 5.0 61.0 1.0 O A:HOH689 5.0 40.2 1.0

J.B.Thoden, H.M.Holden. The Molecular Architecture of Human N-Acetylgalactosamine Kinase. J.Biol.Chem. V. 280 32784 2005.
ISSN: ISSN 0021-9258
PubMed: 16006554
DOI: 10.1074/JBC.M505730200