Atomistry » Chlorine » PDB 2a7d-2aj4 » 2aeo
Atomistry »
  Chlorine »
    PDB 2a7d-2aj4 »
      2aeo »

Chlorine in PDB 2aeo: Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase

Enzymatic activity of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase

All present enzymatic activity of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase:
1.15.1.1;

Protein crystallography data

The structure of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase, PDB code: 2aeo was solved by V.Calderone, A.Casini, S.Mangani, L.Messori, P.L.Orioli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.90 / 1.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 47.207, 50.920, 146.738, 90.00, 90.00, 90.00
R / Rfree (%) 20.2 / 23.6

Other elements in 2aeo:

The structure of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase also contains other interesting chemical elements:

Platinum (Pt) 2 atoms
Copper (Cu) 2 atoms
Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase (pdb code 2aeo). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase, PDB code: 2aeo:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 2aeo

Go back to Chlorine Binding Sites List in 2aeo
Chlorine binding site 1 out of 4 in the Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl284

b:11.6
occ:0.70
 CL2 A:CPT284 0.0 11.6 0.7
PT1 A:CPT284 2.3 16.1 0.7
O A:THR17 3.2 6.3 1.0
NE2 A:HIS19 3.4 13.5 1.0
CA A:GLY31 3.4 7.9 1.0
CD2 A:HIS19 3.5 11.2 1.0
CL1 A:CPT284 3.6 26.0 0.7
CB A:THR17 3.6 6.5 1.0
N A:SER32 3.8 9.0 1.0
C A:THR17 4.0 6.3 1.0
CG2 A:THR17 4.0 6.5 1.0
C A:GLY31 4.0 8.9 1.0
CA A:THR17 4.3 6.6 1.0
OG A:SER32 4.5 14.2 1.0
CE1 A:HIS19 4.5 11.9 1.0
N A:GLY31 4.6 8.0 1.0
OG1 A:THR17 4.6 7.7 1.0
N A:THR17 4.7 6.9 1.0
CG A:HIS19 4.8 8.3 1.0
CA A:SER32 4.9 10.2 1.0
N A:ILE18 5.0 5.2 1.0

Chlorine binding site 2 out of 4 in 2aeo

Go back to Chlorine Binding Sites List in 2aeo
Chlorine binding site 2 out of 4 in the Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl284

b:26.0
occ:0.70
 CL1 A:CPT284 0.0 26.0 0.7
PT1 A:CPT284 2.5 16.1 0.7
CL2 A:CPT284 3.6 11.6 0.7
O A:HOH428 4.3 14.0 1.0
NE2 A:HIS19 4.8 13.5 1.0

Chlorine binding site 3 out of 4 in 2aeo

Go back to Chlorine Binding Sites List in 2aeo
Chlorine binding site 3 out of 4 in the Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl287

b:14.4
occ:0.60
 CL2 B:CPT287 0.0 14.4 0.6
PT1 B:CPT287 2.5 13.4 0.6
CL1 B:CPT287 3.5 7.7 0.6
O B:HOH339 4.0 18.9 1.0
NE2 B:HIS19 4.6 10.4 1.0

Chlorine binding site 4 out of 4 in 2aeo

Go back to Chlorine Binding Sites List in 2aeo
Chlorine binding site 4 out of 4 in the Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Cisplatinated Bovine Cu,Zn Superoxide Dismutase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl287

b:7.7
occ:0.60
 CL1 B:CPT287 0.0 7.7 0.6
PT1 B:CPT287 2.4 13.4 0.6
O B:THR17 3.2 6.1 1.0
NE2 B:HIS19 3.3 10.4 1.0
CD2 B:HIS19 3.4 10.3 1.0
CA B:GLY31 3.5 5.0 1.0
CL2 B:CPT287 3.5 14.4 0.6
OG1 B:THR17 3.7 10.5 1.0
N B:SER32 3.8 5.0 1.0
C B:THR17 4.0 6.3 1.0
C B:GLY31 4.0 5.0 1.0
CB B:THR17 4.4 7.8 1.0
OG B:SER32 4.4 11.2 1.0
CG2 B:THR17 4.4 7.7 1.0
CA B:THR17 4.5 7.1 1.0
CE1 B:HIS19 4.6 9.3 1.0
N B:GLY31 4.7 6.0 1.0
CG B:HIS19 4.7 8.1 1.0
N B:THR17 4.9 6.5 1.0
CA B:SER32 4.9 6.5 1.0
O B:HOH363 4.9 17.9 1.0
CB B:SER32 5.0 7.6 1.0
N B:ILE18 5.0 5.5 1.0
O B:HOH350 5.0 5.8 1.0

Reference:

V.Calderone, A.Casini, S.Mangani, L.Messori, P.L.Orioli. Structural Investigation of Cisplatin-Protein Interactions: Selective Platination of HIS19 in A Cuprozinc Superoxide Dismutase. Angew. Chem. Int. Ed. Engl. V. 45 1267 2006.
ISSN: ISSN 1433-7851
PubMed: 16416478
DOI: 10.1002/ANIE.200502599
Page generated: Thu Jul 10 21:07:33 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy