Chlorine in PDB 2beo: Prfa, Transcriptional Regulator in Listeria Monocytogenes

The structure of Prfa, Transcriptional Regulator in Listeria Monocytogenes, PDB code: 2beo was solved by M.Eiting, G.Hagelueken, W.-D.Schubert, D.W.Heinz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.80 / 2.7
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	55.951, 80.713, 60.965, 90.00, 111.91, 90.00
R / Rfree (%)	24.4 / 28.9

The binding sites of Chlorine atom in the Prfa, Transcriptional Regulator in Listeria Monocytogenes (pdb code 2beo). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Prfa, Transcriptional Regulator in Listeria Monocytogenes, PDB code: 2beo:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Prfa, Transcriptional Regulator in Listeria Monocytogenes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Prfa, Transcriptional Regulator in Listeria Monocytogenes within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1238 b:61.1 occ:1.00 OH A:TYR126 3.1 27.1 1.0 N A:TYR62 3.3 19.9 1.0 NE2 A:GLN61 3.3 30.1 1.0 CD A:GLN61 3.4 28.7 1.0 OE1 A:GLN61 3.6 30.4 1.0 CE2 A:TYR126 3.6 30.3 1.0 CZ A:TYR126 3.8 29.8 1.0 CD2 A:TYR62 3.9 25.1 1.0 O A:TYR62 3.9 22.2 1.0 NZ A:LYS130 3.9 28.2 1.0 CA A:GLN61 4.0 20.8 1.0 C7 A:PG41239 4.1 68.7 1.0 CB A:TYR62 4.1 25.9 1.0 C A:GLN61 4.2 19.3 1.0 CA A:TYR62 4.2 21.4 1.0 CG A:GLN61 4.2 25.5 1.0 CG A:TYR62 4.5 27.3 1.0 C A:TYR62 4.5 20.6 1.0 CB A:GLN61 4.6 24.9 1.0 CD A:LYS130 4.6 24.9 1.0 O A:GLN1240 4.7 60.7 1.0 CE A:LYS130 4.9 28.4 1.0 CD2 A:TYR126 4.9 28.4 1.0 CE2 A:TYR62 4.9 27.4 1.0

Chlorine binding site 2 out of 2 in the Prfa, Transcriptional Regulator in Listeria Monocytogenes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Prfa, Transcriptional Regulator in Listeria Monocytogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1238 b:49.6 occ:0.80 NE2 B:GLN61 2.8 29.6 1.0 OH B:TYR126 3.2 27.1 1.0 N B:TYR62 3.5 20.1 1.0 CE2 B:TYR126 3.8 30.3 1.0 NZ B:LYS130 3.8 28.2 1.0 O B:HOH2012 3.8 42.5 1.0 CD B:GLN61 3.9 27.7 1.0 CZ B:TYR126 4.0 29.8 1.0 CA B:GLN61 4.1 20.9 1.0 CD1 B:TYR62 4.1 27.7 1.0 O B:TYR62 4.2 22.3 1.0 C B:GLN61 4.2 19.4 1.0 CB B:TYR62 4.3 26.4 1.0 CA B:TYR62 4.3 21.4 1.0 CG B:GLN61 4.5 26.0 1.0 CD B:LYS130 4.6 25.0 1.0 CG B:TYR62 4.7 27.4 1.0 OE1 B:GLN61 4.7 28.8 1.0 C B:TYR62 4.7 20.6 1.0 CE B:LYS130 4.7 28.4 1.0 CB B:GLN61 4.8 24.7 1.0

M.Eiting, G.Hagelueken, W.-D.Schubert, D.W.Heinz. The Mutation G145S in Prfa, A Key Virulence Regulator of Listeria Monocytogenes, Increases Dna-Binding Affinity By Stabilizing the Hth Motif Mol.Microbiol. V. 56 433 2005.
ISSN: ISSN 0950-382X
PubMed: 15813735
DOI: 10.1111/J.1365-2958.2005.04561.X