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Atomistry » Chlorine » PDB 2bwx-2c5u » 2c1a | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2bwx-2c5u » 2c1a » |
Chlorine in PDB 2c1a: Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)AmideEnzymatic activity of Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)Amide
All present enzymatic activity of Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)Amide:
2.7.1.37; Protein crystallography data
The structure of Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)Amide, PDB code: 2c1a
was solved by
I.Collins,
J.Caldwell,
T.Fonseca,
A.Donald,
V.Bavetsias,
L.J.Hunter,
M.D.Garrett,
M.G.Rowlands,
G.W.Aherne,
T.G.Davies,
V.Berdini,
S.J.Woodhead,
L.C.A.Seavers,
P.G.Wyatt,
P.Workman,
E.Mcdonald,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)Amide
(pdb code 2c1a). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)Amide, PDB code: 2c1a: Chlorine binding site 1 out of 1 in 2c1aGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Structure of Camp-Dependent Protein Kinase Complexed with Isoquinoline-5-Sulfonic Acid (2-(2-(4-Chlorobenzyloxy)Ethylamino) Ethyl)Amide
![]() Mono view ![]() Stereo pair view
Reference:
I.Collins,
J.Caldwell,
T.Fonseca,
A.Donald,
V.Bavetsias,
L.J.Hunter,
M.D.Garrett,
M.G.Rowlands,
G.W.Aherne,
T.G.Davies,
V.Berdini,
S.J.Woodhead,
D.Davis,
L.C.Seavers,
P.G.Wyatt,
P.Workman,
E.Mcdonald.
Structure-Based Design of Isoquinoline-5-Sulfonamide Inhibitors of Protein Kinase B. Bioorg. Med. Chem. V. 14 1255 2006.
Page generated: Sat Jul 20 06:04:09 2024
ISSN: ISSN 0968-0896 PubMed: 16249095 DOI: 10.1016/J.BMC.2005.09.055 |
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