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Chlorine in PDB 2cni: Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
Enzymatic activity of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
All present enzymatic activity of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B:
3.1.3.48;
3.1.3.48;
Protein crystallography data
The structure of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B, PDB code: 2cni
was solved by
P.J.Ala,
L.Gonneville,
M.Hillman,
M.Becker-Pasha,
E.W.Yue,
B.Douty,
B.Wayland,
P.Polam,
M.L.Crawley,
E.Mclaughlin,
R.B.Sparks,
B.Glass,
A.Takvorian,
A.P.Combs,
T.C.Burn,
G.F.Hollis,
R.Wynn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 8.00 / 2.00 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 67.030, 73.090, 88.110, 90.00, 90.00, 90.00 |
| R / Rfree (%) | n/a / n/a |
Other elements in 2cni:
The structure of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
(pdb code 2cni). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B, PDB code: 2cni:
In total only one binding site of Chlorine was determined in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B, PDB code: 2cni:
Chlorine binding site 1 out of 1 in 2cni
Go back to
Chlorine Binding Sites List in 2cni
Chlorine binding site 1 out
of 1 in the Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
Mono view
Stereo pair view
Mono view
Stereo pair view
|
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Structural Insights Into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B within 5.0Å range:
|
Reference:
P.J.Ala,
L.Gonneville,
M.Hillman,
M.Becker-Pasha,
E.W.Yue,
B.Douty,
B.Wayland,
P.Polam,
M.L.Crawley,
E.Mclaughlin,
R.B.Sparks,
B.Glass,
A.Takvorian,
A.P.Combs,
T.C.Burn,
G.F.Hollis,
R.Wynn.
Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-Containing Inhibitors of Protein- Tyrosine Phosphatase 1B. J.Biol.Chem. V. 281 38013 2006.
ISSN: ISSN 0021-9258
PubMed: 17028182
DOI: 10.1074/JBC.M607913200
Page generated: Sat Jul 20 06:23:15 2024
ISSN: ISSN 0021-9258
PubMed: 17028182
DOI: 10.1074/JBC.M607913200
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