Chlorine in PDB 2csn: Binary Complex of Casein Kinase-1 with CKI7

The structure of Binary Complex of Casein Kinase-1 with CKI7, PDB code: 2csn was solved by R.-M.Xu, X.Cheng, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.00 / 2.50
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	79.100, 79.100, 120.040, 90.00, 90.00, 120.00
R / Rfree (%)	17.8 / n/a

The binding sites of Chlorine atom in the Binary Complex of Casein Kinase-1 with CKI7 (pdb code 2csn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Binary Complex of Casein Kinase-1 with CKI7, PDB code: 2csn:

Chlorine binding site 1 out of 1 in the Binary Complex of Casein Kinase-1 with CKI7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Binary Complex of Casein Kinase-1 with CKI7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl300 b:11.4 occ:1.00 CL5 A:CKI300 0.0 11.4 1.0 C5 A:CKI300 1.7 12.9 1.0 C6 A:CKI300 2.6 19.3 1.0 C10 A:CKI300 2.7 17.3 1.0 C4 A:CKI300 3.1 18.5 1.0 OH A:TYR59 3.5 17.4 1.0 CB A:VAL153 3.6 3.7 1.0 CD1 A:ILE85 3.9 16.9 1.0 OD1 A:ASP154 3.9 22.0 1.0 C7 A:CKI300 4.0 22.4 1.0 C9 A:CKI300 4.0 17.7 1.0 CG1 A:VAL153 4.0 4.0 1.0 CG2 A:VAL153 4.1 2.0 1.0 N A:ASP154 4.3 8.5 1.0 C8 A:CKI300 4.5 26.6 1.0 C3 A:CKI300 4.5 22.4 1.0 CG1 A:ILE85 4.5 9.8 1.0 CA A:VAL153 4.7 2.9 1.0 CZ A:TYR59 4.7 18.5 1.0 CD A:LYS41 4.9 11.7 1.0 C A:VAL153 4.9 5.6 1.0

R.M.Xu, G.Carmel, J.Kuret, X.Cheng. Structural Basis For Selectivity of the Isoquinoline Sulfonamide Family of Protein Kinase Inhibitors. Proc.Natl.Acad.Sci.Usa V. 93 6308 1996.
ISSN: ISSN 0027-8424
PubMed: 8692811
DOI: 10.1073/PNAS.93.13.6308