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Atomistry » Chlorine » PDB 2etd-2f81 » 2f6z | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2etd-2f81 » 2f6z » |
Chlorine in PDB 2f6z: Protein Tyrosine Phosphatase 1B with Sulfamic Acid InhibitorsEnzymatic activity of Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors
All present enzymatic activity of Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors:
3.1.3.48; Protein crystallography data
The structure of Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors, PDB code: 2f6z
was solved by
A.G.Evdokimov,
M.E.Pokross,
S.R.Klopfenstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2f6z:
The structure of Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors
(pdb code 2f6z). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors, PDB code: 2f6z: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 2f6zGo back to![]() ![]()
Chlorine binding site 1 out
of 4 in the Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 4 in 2f6zGo back to![]() ![]()
Chlorine binding site 2 out
of 4 in the Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 4 in 2f6zGo back to![]() ![]()
Chlorine binding site 3 out
of 4 in the Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors
![]() Mono view ![]() Stereo pair view
Chlorine binding site 4 out of 4 in 2f6zGo back to![]() ![]()
Chlorine binding site 4 out
of 4 in the Protein Tyrosine Phosphatase 1B with Sulfamic Acid Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
S.R.Klopfenstein,
A.G.Evdokimov,
A.-O.Colson,
N.T.Fairweather,
J.J.Neuman,
M.B.Maier,
J.L.Gray,
G.S.Gerwe,
G.E.Stake,
B.W.Howard,
J.A.Farmer,
M.E.Pokross,
T.R.Downs,
B.Kasibhatla,
K.G.Peters.
1,2,3,4-Tetrahydroisoquinolinyl Sulfamic Acids As Phosphatase PTP1B Inhibitors Bioorg.Med.Chem.Lett. V. 16 1574 2006.
Page generated: Thu Jul 10 22:05:02 2025
ISSN: ISSN 0960-894X PubMed: 16386905 DOI: 10.1016/J.BMCL.2005.12.051 |
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