Chlorine in PDB 2g9w: Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis

The structure of Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis, PDB code: 2g9w was solved by F.A.Saul, A.Haouz, C.Fiez-Vandal, W.Shepard, P.M.Alzari, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	60.580, 64.330, 75.750, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 25.2

The binding sites of Chlorine atom in the Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis (pdb code 2g9w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis, PDB code: 2g9w:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl251 b:19.9 occ:1.00 OG1 A:THR44 2.9 25.4 1.0 N A:ALA41 3.2 23.1 1.0 CB A:THR44 3.7 23.0 1.0 CA A:LEU40 3.7 25.6 1.0 C A:LEU40 4.0 24.7 1.0 CB A:ALA41 4.0 22.7 1.0 CG2 A:THR44 4.0 20.4 1.0 CD2 A:LEU40 4.0 30.4 1.0 CB A:LEU40 4.2 27.5 1.0 CA A:ALA41 4.2 23.2 1.0 O A:ASP39 4.6 26.8 1.0 CG A:LEU40 4.7 29.0 1.0 O A:ALA41 4.9 22.1 1.0 N A:LEU40 5.0 26.3 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl252 b:16.9 occ:1.00 OG1 B:THR44 3.0 23.9 1.0 N B:ALA41 3.3 24.3 1.0 CB B:THR44 3.6 23.9 1.0 CA B:LEU40 3.8 25.3 1.0 CG2 B:THR44 3.9 24.0 1.0 CD2 B:LEU40 3.9 30.0 1.0 CB B:ALA41 3.9 21.8 1.0 C B:LEU40 4.1 24.9 1.0 CB B:LEU40 4.1 26.2 1.0 CA B:ALA41 4.2 23.9 1.0 CG B:LEU40 4.7 27.9 1.0 O B:ASP39 4.7 27.5 1.0 O B:ALA41 4.9 23.1 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of RV1846C, A Putative Transcriptional Regulatory Protein of Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl253 b:22.9 occ:1.00 O A:HOH313 3.1 33.4 1.0 N B:GLU91 3.2 26.1 1.0 OG B:SER95 3.2 33.4 1.0 NH1 A:ARG75 3.4 24.3 1.0 CB B:SER95 3.5 30.9 1.0 CA B:ALA90 3.6 26.5 1.0 CD A:ARG75 3.7 24.3 1.0 C B:ALA90 3.9 27.1 1.0 CG A:ARG75 3.9 25.2 1.0 CB B:GLU91 4.0 26.4 1.0 CB A:ARG75 4.0 25.7 1.0 CG2 A:VAL79 4.1 23.0 1.0 CB B:ALA90 4.1 26.9 1.0 CA B:GLU91 4.2 26.7 1.0 O A:ARG75 4.2 23.6 1.0 C A:ARG75 4.2 24.0 1.0 CG B:GLU91 4.2 26.7 1.0 N A:ASP76 4.3 25.6 1.0 CZ A:ARG75 4.4 24.6 1.0 CD B:GLU91 4.5 28.0 1.0 O B:GLN89 4.5 26.8 1.0 NE A:ARG75 4.5 25.7 1.0 CA A:ASP76 4.6 25.3 1.0 N B:ALA90 4.6 27.2 1.0 CA A:ARG75 4.7 24.7 1.0 OE1 B:GLU91 4.8 28.0 1.0 OE2 B:GLU91 4.8 28.7 1.0 CA B:SER95 4.9 30.8 1.0 C B:GLN89 5.0 27.0 1.0

C.Sala, A.Haouz, F.A.Saul, I.Miras, I.Rosenkrands, P.M.Alzari, S.T.Cole. Genome-Wide Regulon and Crystal Structure of Blai (RV1846C) From Mycobacterium Tuberculosis Mol.Microbiol. V. 71 1102 2009.
ISSN: ISSN 0950-382X
PubMed: 19154333
DOI: 10.1111/J.1365-2958.2008.06583.X