Chlorine in PDB 2gnq: Structure of WDR5

The structure of Structure of WDR5, PDB code: 2gnq was solved by J.Min, A.Schuetz, A.Allali-Hassani, P.Loppnau, M.Vedadi, J.Weigelt, M.Sundstrom, A.M.Edwards, C.H.Arrowsmith, A.Bochkarev, A.N.Plotnikov, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	62.14 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	50.045, 55.323, 124.308, 90.00, 90.00, 90.00
R / Rfree (%)	14.9 / 19.2

The binding sites of Chlorine atom in the Structure of WDR5 (pdb code 2gnq). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of WDR5, PDB code: 2gnq:

Chlorine binding site 1 out of 1 in the Structure of WDR5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of WDR5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:15.2 occ:1.00 O A:HOH562 3.1 11.7 1.0 ND2 A:ASN287 3.5 12.8 1.0 OD1 A:ASN287 3.6 10.6 1.0 CG A:GLN289 3.8 9.4 1.0 CB A:GLN289 3.9 10.2 1.0 CG A:ASN287 3.9 9.0 1.0 O A:HOH539 4.1 15.5 1.0 O A:HOH727 4.4 23.4 1.0 O A:HOH571 4.4 12.1 1.0 O A:HOH908 4.6 41.9 1.0 O A:HOH713 4.8 29.4 1.0 N A:GLN289 4.9 9.4 1.0

A.Schuetz, A.Allali-Hassani, P.Loppnau, M.Vedadi, A.Bochkarev, A.N.Plotnikov, C.H.Arrowsmith, J.Min. Structural Basis For Molecular Recognition and Presentation of Histone H3 By WDR5. Embo J. V. 25 4245 2006.
ISSN: ISSN 0261-4189
PubMed: 16946699
DOI: 10.1038/SJ.EMBOJ.7601316