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Atomistry » Chlorine » PDB 2gm9-2h9f » 2gtm | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2gm9-2h9f » 2gtm » |
Chlorine in PDB 2gtm: Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579Enzymatic activity of Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579
All present enzymatic activity of Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579:
2.7.11.24; Protein crystallography data
The structure of Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579, PDB code: 2gtm
was solved by
R.L.Walter,
M.J.Mekel,
A.G.Evdokimov,
M.E.Pokross,
M.Sabat,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2gtm:
The structure of Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579
(pdb code 2gtm). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579, PDB code: 2gtm: Chlorine binding site 1 out of 1 in 2gtmGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Mutated Mouse P38 Map Kinase Domain in Complex with Inhibitor Pg- 892579
![]() Mono view ![]() Stereo pair view
Reference:
M.Sabat,
J.C.Vanrens,
M.P.Clark,
T.A.Brugel,
J.Maier,
R.G.Bookland,
M.J.Laufersweiler,
S.K.Laughlin,
A.Golebiowski,
B.De,
L.C.Hsieh,
R.L.Walter,
M.J.Mekel,
M.J.Janusz.
The Development of Novel C-2, C-8, and N-9 Trisubstituted Purines As Inhibitors of Tnf-Alpha Production. Bioorg.Med.Chem.Lett. V. 16 4360 2006.
Page generated: Sat Jul 20 07:39:26 2024
ISSN: ISSN 0960-894X PubMed: 16750367 DOI: 10.1016/J.BMCL.2006.05.050 |
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