Chlorine in PDB 2gv2: MDM2 in Complex with An 8-Mer P53 Peptide Analogue

The structure of MDM2 in Complex with An 8-Mer P53 Peptide Analogue, PDB code: 2gv2 was solved by C.Schubert, K.Sakurai, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.00 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.660, 44.100, 59.150, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Chlorine atom in the MDM2 in Complex with An 8-Mer P53 Peptide Analogue (pdb code 2gv2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the MDM2 in Complex with An 8-Mer P53 Peptide Analogue, PDB code: 2gv2:

Chlorine binding site 1 out of 1 in the MDM2 in Complex with An 8-Mer P53 Peptide Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of MDM2 in Complex with An 8-Mer P53 Peptide Analogue within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl6 b:15.1 occ:1.00 CLL B:6CW6 0.0 15.1 1.0 CH2 B:6CW6 1.7 11.3 1.0 CZ2 B:6CW6 2.7 11.2 1.0 CZ3 B:6CW6 2.7 11.3 1.0 CG2 A:ILE99 3.9 10.1 1.0 CE2 B:6CW6 4.0 10.6 1.0 CE2 A:PHE86 4.0 15.7 1.0 CZ A:PHE86 4.0 16.5 1.0 CE3 B:6CW6 4.0 10.4 1.0 CG A:LEU57 4.0 18.5 1.0 CD1 A:ILE61 4.1 10.0 1.0 CB A:LEU57 4.1 12.8 1.0 CD1 A:ILE103 4.4 14.1 1.0 CZ A:PHE91 4.4 10.4 1.0 CD2 A:LEU57 4.5 14.4 1.0 CD2 B:6CW6 4.5 11.5 1.0 CE1 A:PHE91 4.6 10.8 1.0 CD1 B:LEU9 4.7 18.3 1.0 CG1 A:ILE103 5.0 13.0 1.0 CD1 A:ILE99 5.0 13.1 1.0

K.Sakurai, C.Schubert, D.Kahne. Crystallographic Analysis of An 8-Mer P53 Peptide Analogue Complexed with MDM2. J.Am.Chem.Soc. V. 128 11000 2006.
ISSN: ISSN 0002-7863
PubMed: 16925398
DOI: 10.1021/JA063102J