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Atomistry » Chlorine » PDB 2h9j-2hr2 » 2hb3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2h9j-2hr2 » 2hb3 » |
Chlorine in PDB 2hb3: Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579Enzymatic activity of Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579
All present enzymatic activity of Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579:
3.4.23.4; Protein crystallography data
The structure of Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579, PDB code: 2hb3
was solved by
A.Y.Kovalevsky,
I.T.Weber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2hb3:
The structure of Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579
(pdb code 2hb3). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579, PDB code: 2hb3: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 2hb3Go back to![]() ![]()
Chlorine binding site 1 out
of 3 in the Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 3 in 2hb3Go back to![]() ![]()
Chlorine binding site 2 out
of 3 in the Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 3 in 2hb3Go back to![]() ![]()
Chlorine binding site 3 out
of 3 in the Wild-Type Hiv-1 Protease in Complex with Potent Inhibitor GRL06579
![]() Mono view ![]() Stereo pair view
Reference:
A.K.Ghosh,
P.R.Sridhar,
S.Leshchenko,
A.K.Hussain,
J.Li,
A.Y.Kovalevsky,
D.E.Walters,
J.E.Wedekind,
V.Grum-Tokars,
D.Das,
Y.Koh,
K.Maeda,
H.Gatanaga,
I.T.Weber,
H.Mitsuya.
Structure-Based Design of Novel Hiv-1 Protease Inhibitors to Combat Drug Resistance. J.Med.Chem. V. 49 5252 2006.
Page generated: Thu Jul 10 22:31:36 2025
ISSN: ISSN 0022-2623 PubMed: 16913714 DOI: 10.1021/JM060561M |
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