Atomistry » Chlorine » PDB 2ii4-2iws » 2iux
Atomistry »
  Chlorine »
    PDB 2ii4-2iws »
      2iux »

Chlorine in PDB 2iux: Human Tace Mutant G1234

Enzymatic activity of Human Tace Mutant G1234

All present enzymatic activity of Human Tace Mutant G1234:
3.4.15.1;

Protein crystallography data

The structure of Human Tace Mutant G1234, PDB code: 2iux was solved by J.M.Watermeyer, B.T.Swell, R.Natesh, H.R.Corradi, K.R.Acharya, E.D.Sturrock, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.0 / 2.8
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 56.436, 85.149, 133.424, 90.00, 90.00, 90.00
R / Rfree (%) 20.06 / 23.69

Other elements in 2iux:

The structure of Human Tace Mutant G1234 also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human Tace Mutant G1234 (pdb code 2iux). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Tace Mutant G1234, PDB code: 2iux:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 2iux

Go back to Chlorine Binding Sites List in 2iux
Chlorine binding site 1 out of 2 in the Human Tace Mutant G1234


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Tace Mutant G1234 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1622

b:15.9
occ:1.00
NE A:ARG186 3.1 13.1 1.0
NH1 A:ARG186 3.3 13.4 1.0
NH1 A:ARG489 3.3 12.7 1.0
CZ2 A:TRP486 3.3 9.8 1.0
NE1 A:TRP485 3.4 11.3 1.0
CZ A:ARG186 3.6 13.0 1.0
CB A:ASP507 3.8 11.4 1.0
CH2 A:TRP486 3.8 11.7 1.0
NE A:ARG489 3.8 10.7 1.0
CZ A:ARG489 3.8 11.5 1.0
CE2 A:TRP486 4.2 9.2 1.0
CD A:ARG186 4.2 13.2 1.0
CZ2 A:TRP182 4.2 20.2 1.0
CE2 A:TRP485 4.3 11.2 1.0
CD1 A:TRP485 4.3 13.1 1.0
CZ2 A:TRP485 4.5 12.0 1.0
O A:ASP507 4.5 11.3 1.0
CG A:ASP507 4.5 12.9 1.0
NE1 A:TRP486 4.6 8.9 1.0
C A:ASP507 4.8 10.6 1.0
CA A:ASP507 4.8 10.4 1.0
NE1 A:TRP182 4.8 21.6 1.0
CE2 A:TRP182 4.9 21.0 1.0
NH2 A:ARG489 4.9 14.7 1.0
CZ3 A:TRP486 4.9 11.0 1.0
NH2 A:ARG186 4.9 12.2 1.0
CD A:ARG489 5.0 10.3 1.0

Chlorine binding site 2 out of 2 in 2iux

Go back to Chlorine Binding Sites List in 2iux
Chlorine binding site 2 out of 2 in the Human Tace Mutant G1234


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Tace Mutant G1234 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1623

b:14.3
occ:1.00
OH A:TYR224 3.0 13.4 1.0
O A:HOH2014 3.1 15.3 1.0
NE A:ARG522 3.2 15.2 1.0
CB A:ARG522 3.4 7.0 1.0
CB A:PRO407 3.5 10.3 1.0
CE1 A:TYR224 3.6 10.9 1.0
CB A:PRO519 3.6 8.3 1.0
NH2 A:ARG522 3.6 15.8 1.0
N A:ARG522 3.6 8.4 1.0
CZ A:TYR224 3.7 12.5 1.0
CG A:PRO407 3.8 11.1 1.0
CE A:MET223 3.8 13.6 1.0
CZ A:ARG522 3.8 16.1 1.0
CG2 A:ILE521 3.8 8.4 1.0
CA A:ARG522 3.9 9.4 1.0
CG A:ARG522 4.0 7.9 1.0
CD A:ARG522 4.2 11.9 1.0
C A:ILE521 4.5 9.8 1.0
CG A:PRO519 4.6 7.8 1.0
C A:PRO519 4.7 9.3 1.0
CA A:PRO519 4.7 9.0 1.0
O A:PRO519 4.8 10.1 1.0
N A:ILE521 4.8 10.6 1.0
CD1 A:TYR224 4.8 8.5 1.0
SD A:MET223 4.8 13.0 1.0
CD A:PRO407 4.8 10.8 1.0
CA A:PRO407 5.0 10.1 1.0
CA A:ILE521 5.0 8.8 1.0
CE2 A:TYR224 5.0 11.4 1.0

Reference:

J.M.Watermeyer, B.T.Sewell, S.L.Schwager, R.Natesh, H.R.Corradi, K.R.Acharya, E.D.Sturrock. Structure of Testis Ace Glycosylation Mutants and Evidence For Conserved Domain Movement. Biochemistry V. 45 12654 2006.
ISSN: ISSN 0006-2960
PubMed: 17042482
DOI: 10.1021/BI061146Z
Page generated: Thu Jul 10 22:52:00 2025

Last articles

Mg in 5L5W
Mg in 5L5Y
Mg in 5L5X
Mg in 5L5V
Mg in 5L5U
Mg in 5L5T
Mg in 5L5S
Mg in 5L5R
Mg in 5L5P
Mg in 5L5Q
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy