Atomistry » Chlorine » PDB 2ol4-2oud » 2ot1
Atomistry »
  Chlorine »
    PDB 2ol4-2oud »
      2ot1 »

Chlorine in PDB 2ot1: Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor

Enzymatic activity of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor

All present enzymatic activity of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor:
4.1.2.13;

Protein crystallography data

The structure of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor, PDB code: 2ot1 was solved by M.St-Jean, T.Izard, J.Sygusch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.05
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 84.780, 103.445, 83.601, 90.00, 98.66, 90.00
R / Rfree (%) 14.9 / 19.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor (pdb code 2ot1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor, PDB code: 2ot1:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 2ot1

Go back to Chlorine Binding Sites List in 2ot1
Chlorine binding site 1 out of 4 in the Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl3001

b:56.2
occ:1.00
 CLA A:N3P3001 0.0 56.2 1.0
CAS A:N3P3001 1.7 57.0 1.0
CAH A:N3P3001 2.7 56.0 1.0
CAI A:N3P3001 2.7 57.2 1.0
O A:HOH3184 3.7 51.0 1.0
CAJ A:N3P3001 4.0 56.4 1.0
CAK A:N3P3001 4.0 57.1 1.0
CAT A:N3P3001 4.5 56.2 1.0
O A:HOH3447 4.7 41.5 1.0

Chlorine binding site 2 out of 4 in 2ot1

Go back to Chlorine Binding Sites List in 2ot1
Chlorine binding site 2 out of 4 in the Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl3002

b:61.0
occ:1.00
 CLA B:N3P3002 0.0 61.0 1.0
CAS B:N3P3002 1.7 61.3 1.0
CAH B:N3P3002 2.7 60.5 1.0
CAI B:N3P3002 2.7 60.8 1.0
CAK B:N3P3002 4.0 60.2 1.0
CAJ B:N3P3002 4.0 60.4 1.0
CAT B:N3P3002 4.5 59.8 1.0
O B:HOH3168 4.6 54.0 1.0
O B:HOH3344 4.8 60.7 1.0

Chlorine binding site 3 out of 4 in 2ot1

Go back to Chlorine Binding Sites List in 2ot1
Chlorine binding site 3 out of 4 in the Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl3003

b:60.9
occ:1.00
 CLA C:N3P3003 0.0 60.9 1.0
CAS C:N3P3003 1.7 60.9 1.0
CAH C:N3P3003 2.7 61.0 1.0
CAI C:N3P3003 2.7 60.8 1.0
CAK C:N3P3003 4.0 59.4 1.0
CAJ C:N3P3003 4.0 59.8 1.0
CAT C:N3P3003 4.5 58.6 1.0
O C:HOH3010 4.9 56.6 1.0

Chlorine binding site 4 out of 4 in 2ot1

Go back to Chlorine Binding Sites List in 2ot1
Chlorine binding site 4 out of 4 in the Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Fructose-1,6-Bisphosphate Aldolase From Rabbit Muscle in Complex with Naphthol As-E Phosphate, A Competitive Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl3004

b:50.7
occ:1.00
 CLA D:N3P3004 0.0 50.7 1.0
CAS D:N3P3004 1.7 50.7 1.0
CAI D:N3P3004 2.7 50.5 1.0
CAH D:N3P3004 2.7 50.0 1.0
O D:HOH3176 3.2 60.4 1.0
CAJ D:N3P3004 4.0 49.0 1.0
CAK D:N3P3004 4.0 50.1 1.0
CAT D:N3P3004 4.5 49.0 1.0

Reference:

M.St-Jean, T.Izard, J.Sygusch. A Hydrophobic Pocket in the Active Site of Glycolytic Aldolase Mediates Interactions with Wiskott-Aldrich Syndrome Protein. J.Biol.Chem. V. 282 14309 2007.
ISSN: ISSN 0021-9258
PubMed: 17329259
DOI: 10.1074/JBC.M611505200
Page generated: Sat Jul 20 09:43:52 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy