Chlorine in PDB 2pa1: Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin

The structure of Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin, PDB code: 2pa1 was solved by J.Uppenberg, L.Shrestha, J.Elkins, N.Burgess-Brown, E.Salah, G.Bunkoczi, E.Papagrigoriou, A.C.W.Pike, A.P.Turnbull, E.Ugochukwu, C.Umeano, F.Vondelft, J.Weigelt, C.H.Arrowsmith, A.Edwards, M.Sundstrom, D.A.Doyle, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.39 / 1.70
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	58.770, 58.770, 52.340, 90.00, 90.00, 120.00
R / Rfree (%)	19.2 / 25.3

The binding sites of Chlorine atom in the Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin (pdb code 2pa1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin, PDB code: 2pa1:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:61.3 occ:1.00 OG1 A:THR84 2.9 32.3 1.0 N A:SER0 3.3 35.7 1.0 N A:THR84 3.5 30.9 1.0 N A:SER85 3.5 27.5 1.0 CA A:SER0 3.7 35.3 1.0 CB A:SER85 4.0 25.7 1.0 CB A:THR84 4.1 31.0 1.0 CA A:THR84 4.1 30.6 1.0 C A:THR84 4.2 29.3 1.0 CB A:SER0 4.2 35.6 1.0 CA A:SER85 4.3 25.6 1.0 CG2 A:ILE83 4.4 31.1 1.0 CA A:ILE83 4.5 31.7 1.0 C A:ILE83 4.5 31.6 1.0 CG2 A:THR84 4.9 31.9 1.0 CB A:ILE83 5.0 31.9 1.0

Chlorine binding site 2 out of 2 in the Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:67.2 occ:1.00 OG1 A:THR4 3.4 31.2 1.0 N A:THR4 3.9 29.9 1.0 CA A:LEU3 4.0 30.1 1.0 C A:LEU3 4.0 30.2 1.0 O A:ALA2 4.1 29.4 1.0 CB A:THR4 4.3 29.9 1.0 N A:LEU3 4.3 29.7 1.0 C A:ALA2 4.3 30.3 1.0 CA A:THR4 4.7 30.4 1.0 O A:LEU3 4.7 30.0 1.0 O A:HOH207 4.8 57.4 1.0 O A:HOH260 4.8 40.3 1.0 CB A:ALA2 4.9 30.9 1.0

J.Uppenberg, L.Shrestha, J.Elkins, N.Burgess-Brown, E.Salah, G.Bunkoczi, E.Papagrigoriou, A.C.W.Pike, A.P.Turnbull, E.Ugochukwu, C.Umeano, F.Von Delft, J.Weigelt, C.H.Arrowsmith, A.Edwards, M.Sundstrom, D.A.Doyle. Structure of the Pdz Domain of Human PDLIM2 Bound to A C-Terminal Extension From Human Beta-Tropomyosin. To Be Published.