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Atomistry » Chlorine » PDB 2pgc-2px2 » 2pr3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2pgc-2px2 » 2pr3 » |
Chlorine in PDB 2pr3: Factor Xa InhibitorEnzymatic activity of Factor Xa Inhibitor
All present enzymatic activity of Factor Xa Inhibitor:
3.4.21.6; Protein crystallography data
The structure of Factor Xa Inhibitor, PDB code: 2pr3
was solved by
E.Zhang,
J.T.Kohrt,
C.F.Bigge,
B.C.Finzel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2pr3:
The structure of Factor Xa Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Factor Xa Inhibitor
(pdb code 2pr3). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Factor Xa Inhibitor, PDB code: 2pr3: Chlorine binding site 1 out of 1 in 2pr3Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Factor Xa Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
C.A.Van Huis,
C.F.Bigge,
A.Casimiro-Garcia,
W.L.Cody,
D.A.Dudley,
K.J.Filipski,
R.J.Heemstra,
J.T.Kohrt,
L.S.Narasimhan,
R.P.Schaum,
E.Zhang,
J.W.Bryant,
S.Haarer,
N.Janiczek,
R.J.Leadley,
T.Mcclanahan,
J.Thomas Peterson,
K.M.Welch,
J.J.Edmunds.
Structure-Based Drug Design of Pyrrolidine-1, 2-Dicarboxamides As A Novel Series of Orally Bioavailable Factor Xa Inhibitors Chem.Biol.Drug Des. V. 69 444 2007.
Page generated: Sat Jul 20 10:16:26 2024
ISSN: ISSN 1747-0277 PubMed: 17581239 DOI: 10.1111/J.1747-0285.2007.00520.X |
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