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Atomistry » Chlorine » PDB 2rha-2uxn » 2rl5 » |
Chlorine in PDB 2rl5: Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine InhibitorEnzymatic activity of Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine Inhibitor
All present enzymatic activity of Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine Inhibitor:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine Inhibitor, PDB code: 2rl5
was solved by
D.A.Whittington,
A.M.Long,
P.Rose,
H.Zhao,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine Inhibitor
(pdb code 2rl5). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine Inhibitor, PDB code: 2rl5: Chlorine binding site 1 out of 1 in 2rl5Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of the VEGFR2 Kinase Domain in Complex with A 2,3- Dihydro-1,4-Benzoxazine Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
D.S.La,
J.Belzile,
J.V.Bready,
A.Coxon,
T.Demelfi,
N.Doerr,
J.Estrada,
J.C.Flynn,
S.R.Flynn,
R.F.Graceffa,
S.P.Harriman,
J.F.Larrow,
A.M.Long,
M.W.Martin,
M.J.Morrison,
V.F.Patel,
P.M.Roveto,
L.Wang,
M.M.Weiss,
D.A.Whittington,
Y.Teffera,
Z.Zhao,
A.J.Polverino,
J.C.Harmange.
Novel 2,3-Dihydro-1,4-Benzoxazines As Potent and Orally Bioavailable Inhibitors of Tumor-Driven Angiogenesis. J.Med.Chem. V. 51 1695 2008.
Page generated: Sat Jul 20 11:21:43 2024
ISSN: ISSN 0022-2623 PubMed: 18311900 DOI: 10.1021/JM701129J |
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