Atomistry » Chlorine » PDB 2uxp-2v79 » 2uzc
Atomistry »
  Chlorine »
    PDB 2uxp-2v79 »
      2uzc »

Chlorine in PDB 2uzc: Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1

Protein crystallography data

The structure of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1, PDB code: 2uzc was solved by G.Bunkoczi, J.Elkins, E.Salah, N.Burgess-Brown, E.Papagrigoriou, A.C.W.Pike, A.Turnbull, O.Gileadi, F.Von Delft, C.H.Arrowsmith, A.Edwards, M.Sundstrom, J.Weigelt, D.Doyle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.50
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 61.250, 36.474, 88.706, 90.00, 99.15, 90.00
R / Rfree (%) 16.3 / 21.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 (pdb code 2uzc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1, PDB code: 2uzc:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 2uzc

Go back to Chlorine Binding Sites List in 2uzc
Chlorine binding site 1 out of 6 in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1088

b:39.1
occ:1.00
 OG B:SER31 2.9 19.1 1.0
O B:HOH2019 3.0 44.6 1.0
NE B:ARG17 3.0 26.5 1.0
NH2 B:ARG17 3.3 32.4 1.0
CB B:SER31 3.5 17.1 1.0
CZ B:ARG17 3.6 26.1 1.0
CB B:SER32 4.0 22.9 1.0
CB B:ARG17 4.0 15.6 1.0
O B:SER31 4.1 20.0 1.0
CD B:ARG17 4.1 21.8 1.0
C B:SER31 4.1 19.5 1.0
NE2 B:GLN19 4.2 23.2 0.5
NE A:ARG45 4.4 14.6 0.5
O B:HOH2032 4.4 29.7 1.0
CA B:SER31 4.5 14.4 1.0
O B:HOH2018 4.5 27.7 1.0
N B:SER32 4.6 15.7 1.0
CG B:GLN19 4.6 22.8 0.5
CG B:ARG17 4.6 20.3 1.0
CD B:GLN19 4.8 20.2 0.5
NH2 A:ARG45 4.8 18.6 0.5
O B:LEU18 4.8 16.2 1.0
CZ A:ARG45 4.9 16.3 0.5
OG B:SER32 4.9 23.7 1.0
CA B:SER32 4.9 15.9 1.0
NH1 B:ARG17 4.9 23.6 1.0

Chlorine binding site 2 out of 6 in 2uzc

Go back to Chlorine Binding Sites List in 2uzc
Chlorine binding site 2 out of 6 in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1088

b:25.9
occ:1.00
 OG C:SER31 3.0 15.2 1.0
O C:HOH2045 3.1 43.6 1.0
NE C:ARG17 3.1 19.8 1.0
NH2 C:ARG17 3.3 20.9 1.0
NE2 C:GLN19 3.4 22.9 1.0
CB C:SER31 3.5 15.1 1.0
CZ C:ARG17 3.7 22.4 1.0
O C:SER31 4.2 18.5 1.0
CB C:ARG17 4.2 16.6 1.0
CD C:ARG17 4.2 19.6 1.0
C C:SER31 4.2 17.4 1.0
CG C:GLN19 4.3 18.3 1.0
CB C:SER32 4.3 18.7 1.0
CD C:GLN19 4.3 21.3 1.0
CA C:SER31 4.6 12.9 1.0
N C:SER32 4.7 15.6 1.0
O C:HOH2023 4.7 24.8 1.0
CG C:ARG17 4.8 15.6 1.0
O C:LEU18 4.9 13.2 1.0

Chlorine binding site 3 out of 6 in 2uzc

Go back to Chlorine Binding Sites List in 2uzc
Chlorine binding site 3 out of 6 in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1088

b:30.3
occ:1.00
 O D:HOH2086 2.4 34.8 1.0
OG D:SER52 2.8 19.4 1.0
N D:GLY55 3.0 21.0 1.0
CA D:GLY55 3.6 25.5 1.0
O D:ASN78 3.6 14.6 1.0
N D:ASP54 3.6 17.9 1.0
CA D:MET79 3.7 16.2 1.0
CB D:SER52 3.8 14.7 1.0
C D:SER52 3.8 15.4 1.0
N D:THR80 3.8 12.4 1.0
C D:ASN78 3.8 12.9 1.0
C D:MET79 3.8 15.3 1.0
O D:SER52 3.9 14.2 1.0
O D:HOH2062 3.9 39.7 1.0
N D:MET79 3.9 15.8 1.0
C D:ILE53 4.0 14.3 1.0
N D:ILE53 4.0 16.1 1.0
CG2 D:THR80 4.0 14.8 0.5
C D:ASP54 4.0 21.0 1.0
OG1 D:THR80 4.1 17.2 0.5
CA D:ASP54 4.2 25.6 1.0
CA D:ILE53 4.2 15.8 1.0
CB D:ASN78 4.2 17.1 1.0
CA D:SER52 4.4 14.9 1.0
C D:GLY55 4.5 29.3 1.0
O D:MET79 4.5 15.4 1.0
CB D:THR80 4.7 14.6 0.5
OG1 D:THR80 4.7 17.6 0.5
CA D:ASN78 4.7 13.2 1.0
O D:ILE53 4.7 18.9 1.0
CB D:THR80 4.8 15.4 0.5
N D:ILE56 4.8 17.7 1.0
O D:HOH2007 4.8 30.6 1.0
CA D:THR80 4.9 13.1 1.0

Chlorine binding site 4 out of 6 in 2uzc

Go back to Chlorine Binding Sites List in 2uzc
Chlorine binding site 4 out of 6 in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1089

b:33.8
occ:1.00
 O D:HOH2046 2.8 38.6 1.0
O D:HOH2047 3.0 25.4 1.0
N D:VAL9 3.1 20.3 1.0
CA D:LEU8 3.6 16.2 1.0
CG D:LYS38 3.8 14.3 1.0
C D:LEU8 3.8 19.4 1.0
CB D:VAL9 3.9 21.5 1.0
CB D:LYS38 3.9 16.2 1.0
CA D:VAL9 4.0 20.7 1.0
CB D:LEU8 4.0 18.2 1.0
CG2 D:VAL9 4.0 27.2 1.0
O D:VAL9 4.0 19.2 1.0
CD D:LYS38 4.2 19.2 1.0
O D:HOH2050 4.2 36.7 1.0
NZ D:LYS38 4.2 37.3 1.0
CD2 D:LEU8 4.3 14.8 1.0
C D:VAL9 4.5 18.8 1.0
CA D:LYS38 4.7 16.1 1.0
O D:SER7 4.8 20.1 1.0
CG D:LEU8 4.8 16.7 1.0
CE D:LYS38 4.8 23.7 1.0
O D:LYS38 4.9 14.5 1.0
N D:LEU8 4.9 14.6 1.0
O D:HOH2017 5.0 51.1 1.0

Chlorine binding site 5 out of 6 in 2uzc

Go back to Chlorine Binding Sites List in 2uzc
Chlorine binding site 5 out of 6 in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl1088

b:31.8
occ:1.00
 OG E:SER31 3.0 17.5 1.0
NE E:ARG17 3.1 21.3 1.0
NE2 E:GLN19 3.3 28.6 1.0
NH2 E:ARG17 3.6 29.1 1.0
CB E:SER31 3.6 17.6 1.0
CZ E:ARG17 3.8 22.9 1.0
O E:HOH2020 3.8 22.8 1.0
CB E:ARG17 4.0 16.2 1.0
CD E:ARG17 4.1 21.9 1.0
O E:SER31 4.2 17.9 1.0
CG E:GLN19 4.2 17.5 1.0
CD E:GLN19 4.2 24.4 1.0
CB E:SER32 4.3 21.3 1.0
C E:SER31 4.3 18.4 1.0
NE C:ARG45 4.3 24.1 1.0
O C:HOH2066 4.4 42.6 1.0
CG E:ARG17 4.6 19.3 1.0
CA E:SER31 4.6 16.0 1.0
N E:SER32 4.7 15.9 1.0
CD C:ARG45 4.7 16.8 1.0
O E:LEU18 4.7 16.2 1.0
CZ C:ARG45 5.0 19.5 1.0

Chlorine binding site 6 out of 6 in 2uzc

Go back to Chlorine Binding Sites List in 2uzc
Chlorine binding site 6 out of 6 in the Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Structure of Human PDLIM5 in Complex with the C-Terminal Peptide of Human Alpha-Actinin-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl1089

b:27.2
occ:1.00
 OG E:SER52 2.8 23.6 1.0
N E:GLY55 3.2 23.1 1.0
O E:HOH2051 3.3 25.3 1.0
CG2 E:THR80 3.6 16.7 0.5
O E:ASN78 3.6 20.0 1.0
CB E:SER52 3.7 20.5 1.0
N E:THR80 3.7 17.0 1.0
CA E:MET79 3.7 15.8 1.0
N E:ASP54 3.7 18.0 1.0
C E:MET79 3.8 18.7 1.0
O E:SER52 3.8 16.5 1.0
C E:SER52 3.8 16.5 1.0
CA E:GLY55 3.8 27.0 1.0
C E:ASN78 3.9 15.9 1.0
N E:MET79 3.9 16.3 1.0
OG1 E:THR80 3.9 22.2 0.5
N E:ILE53 4.0 15.4 1.0
C E:ILE53 4.1 18.6 1.0
C E:ASP54 4.2 25.7 1.0
CA E:ILE53 4.2 16.6 1.0
CA E:ASP54 4.3 23.3 1.0
CA E:SER52 4.4 16.7 1.0
CB E:ASN78 4.4 20.0 1.0
O E:MET79 4.5 20.2 1.0
CB E:THR80 4.5 20.9 0.5
CB E:THR80 4.5 20.4 0.5
OG1 E:THR80 4.5 19.5 0.5
CA E:THR80 4.7 17.7 1.0
O E:HOH2071 4.7 41.4 1.0
C E:GLY55 4.8 26.0 1.0
O E:ILE53 4.8 19.4 1.0
CA E:ASN78 4.8 17.4 1.0
N E:ILE56 5.0 21.0 1.0
O E:HOH2008 5.0 34.4 1.0

Reference:

J.M.Elkins, C.Gileadi, L.Shrestha, C.Phillips, J.Wang, J.R.Muniz, D.A.Doyle. Unusual Binding Interactions in Pdz Domain Crystal Structures Help Explain Binding Mechanisms. Protein Sci. V. 19 731 2010.
ISSN: ESSN 1469-896X
PubMed: 20120020
DOI: 10.1002/PRO.349
Page generated: Sat Jul 20 11:29:29 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy