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Atomistry » Chlorine » PDB 2vvc-2w26 » 2vwu | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2vvc-2w26 » 2vwu » |
Chlorine in PDB 2vwu: EPHB4 Kinase Domain Inhibitor ComplexEnzymatic activity of EPHB4 Kinase Domain Inhibitor Complex
All present enzymatic activity of EPHB4 Kinase Domain Inhibitor Complex:
2.7.10.1; Protein crystallography data
The structure of EPHB4 Kinase Domain Inhibitor Complex, PDB code: 2vwu
was solved by
J.Read,
C.A.Brassington,
I.Green,
E.J.Mccall,
A.L.Valentine,
D.Barratt,
S.Rowsell,
M.Packer,
M.Mcalister,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the EPHB4 Kinase Domain Inhibitor Complex
(pdb code 2vwu). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the EPHB4 Kinase Domain Inhibitor Complex, PDB code: 2vwu: Chlorine binding site 1 out of 1 in 2vwuGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the EPHB4 Kinase Domain Inhibitor Complex
![]() Mono view ![]() Stereo pair view
Reference:
C.Bardelle,
D.Cross,
S.Davenport,
J.G.Kettle,
E.J.Ko,
A.G.Leach,
A.Mortlock,
J.Read,
N.J.Roberts,
P.Robins,
E.J.Williams.
Inhibitors of the Tyrosine Kinase EPHB4. Part 1: Structure-Based Design and Optimization of A Series of 2,4-Bis-Anilinopyrimidines Bioorg.Med.Chem.Lett. V. 18 2776 2008.
Page generated: Fri Jul 11 01:05:31 2025
ISSN: ISSN 0960-894X PubMed: 18434142 DOI: 10.1016/J.BMCL.2008.04.015 |
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