Chlorine in PDB 2vx8: VAMP7 Longin Domain Hrb Peptide Complex

The structure of VAMP7 Longin Domain Hrb Peptide Complex, PDB code: 2vx8 was solved by P.R.Evans, D.J.Owen, J.P.Luzio, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.71 / 2.20
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	105.514, 115.102, 55.440, 90.00, 90.00, 90.00
R / Rfree (%)	22 / 28

The binding sites of Chlorine atom in the VAMP7 Longin Domain Hrb Peptide Complex (pdb code 2vx8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the VAMP7 Longin Domain Hrb Peptide Complex, PDB code: 2vx8:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the VAMP7 Longin Domain Hrb Peptide Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of VAMP7 Longin Domain Hrb Peptide Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1158 b:28.5 occ:1.00 O B:HOH2030 2.9 28.9 1.0 CE1 B:HIS96 3.5 26.7 1.0 OG1 B:THR87 3.7 19.9 1.0 ND1 B:HIS96 3.8 24.9 1.0 CG2 B:THR87 3.9 27.1 1.0 CD1 B:LEU94 4.0 17.9 1.0 CG2 A:VAL24 4.1 28.7 1.0 CB B:THR87 4.1 24.9 1.0 CE1 B:PHE119 4.4 27.6 1.0 NE2 B:HIS96 4.7 27.1 1.0 CG2 A:THR21 5.0 49.1 1.0

Chlorine binding site 2 out of 3 in the VAMP7 Longin Domain Hrb Peptide Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of VAMP7 Longin Domain Hrb Peptide Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1159 b:29.3 occ:1.00 ND1 A:HIS90 3.1 26.3 1.0 N B:LEU38 3.2 25.4 1.0 O A:HIS90 3.7 26.1 1.0 CD2 A:TYR93 3.7 22.5 1.0 CG B:LEU38 3.7 27.2 1.0 CB B:LEU38 3.8 27.0 1.0 CA B:THR37 3.8 25.1 1.0 C B:THR37 4.0 24.3 1.0 CD1 B:LEU38 4.0 23.0 1.0 CE1 A:HIS90 4.0 28.2 1.0 CG A:HIS90 4.1 24.7 1.0 CA B:LEU38 4.1 26.3 1.0 CB A:HIS90 4.2 21.2 1.0 CG2 B:THR37 4.2 25.4 1.0 CZ A:PHE95 4.3 23.4 1.0 C A:HIS90 4.3 23.3 1.0 O B:PRO36 4.4 23.1 1.0 CE2 A:TYR93 4.5 23.4 1.0 CE2 A:PHE95 4.5 20.6 1.0 CG A:TYR93 4.6 21.6 1.0 CB A:TYR93 4.6 20.1 1.0 CB B:THR37 4.6 24.8 1.0 O B:LEU38 4.7 26.1 1.0 N A:GLY91 4.8 26.2 1.0 CA A:HIS90 4.9 23.1 1.0 C B:LEU38 4.9 26.6 1.0 N B:THR37 5.0 22.6 1.0

Chlorine binding site 3 out of 3 in the VAMP7 Longin Domain Hrb Peptide Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of VAMP7 Longin Domain Hrb Peptide Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1159 b:58.4 occ:1.00 N D:LEU38 3.1 49.0 1.0 CA D:THR37 3.4 49.2 1.0 ND1 D:HIS90 3.5 34.4 1.0 CD2 D:TYR93 3.7 34.0 1.0 C D:THR37 3.7 49.1 1.0 O C:HOH2005 3.8 43.6 1.0 CB D:THR37 3.8 49.7 1.0 CE2 D:TYR93 4.0 36.5 1.0 CE1 D:HIS90 4.1 36.6 1.0 CB D:LEU38 4.1 48.6 1.0 CA D:LEU38 4.1 50.1 1.0 O D:HIS90 4.1 30.8 1.0 CG D:LEU38 4.2 47.6 1.0 O D:HOH2030 4.3 44.1 1.0 CG D:HIS90 4.4 31.5 1.0 O D:LEU38 4.5 53.5 1.0 C D:HIS90 4.5 31.0 1.0 O D:PRO36 4.5 49.8 1.0 CG2 D:THR37 4.5 47.2 1.0 CA D:GLY91 4.6 32.5 1.0 CD1 D:LEU38 4.6 41.1 1.0 N D:THR37 4.7 49.0 1.0 N D:GLY91 4.7 32.3 1.0 CB D:HIS90 4.7 30.5 1.0 CG D:TYR93 4.8 33.6 1.0 C D:LEU38 4.8 51.9 1.0 O C:HOH2003 4.8 45.9 1.0 O D:THR37 5.0 49.3 1.0 OG1 D:THR37 5.0 50.3 1.0

P.R.Pryor, L.Jackson, S.R.Gray, M.A.Edeling, A.Thompson, C.M.Sanderson, P.R.Evans, D.J.Owen, J.P.Luzio. Molecular Basis For the Sorting of the Snare VAMP7 Into Endocytic Clathrin-Coated Vesicles By the Arfgap Hrb. Cell(Cambridge,Mass.) V. 134 817 2008.
ISSN: ISSN 0092-8674
PubMed: 18775314
DOI: 10.1016/J.CELL.2008.07.023