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Chlorine in PDB 2vya: Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750
Enzymatic activity of Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750
All present enzymatic activity of Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750:
3.5.1.4;
3.5.1.4;
Protein crystallography data
The structure of Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750, PDB code: 2vya
was solved by
M.Mileni,
D.S.Johnson,
Z.Wang,
D.S.Everdeen,
M.Liimatta,
B.Pabst,
K.Bhattacharya,
R.A.Nugent,
S.Kamtekar,
B.F.Cravatt,
K.Ahn,
R.C.Stevens,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 38.26 / 2.75 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 103.690, 103.690, 253.870, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 18.8 / 23.9 |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750
(pdb code 2vya). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750, PDB code: 2vya:
In total only one binding site of Chlorine was determined in the Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750, PDB code: 2vya:
Chlorine binding site 1 out of 1 in 2vya
Go back to
Chlorine Binding Sites List in 2vya
Chlorine binding site 1 out
of 1 in the Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Fatty Acid Amide Hydrolase Conjugated with the Drug-Like Inhibitor Pf-750 within 5.0Å range:
|
Reference:
M.Mileni,
D.S.Johnson,
Z.Wang,
D.S.Everdeen,
M.Liimatta,
B.Pabst,
K.Bhattacharya,
R.A.Nugent,
S.Kamtekar,
B.F.Cravatt,
K.Ahn,
R.C.Stevens.
Structure-Guided Inhibitor Design For Human Faah By Interspecies Active Site Conversion. Proc.Natl.Acad.Sci.Usa V. 105 12820 2008.
ISSN: ISSN 0027-8424
PubMed: 18753625
DOI: 10.1073/PNAS.0806121105
Page generated: Fri Jul 11 01:07:45 2025
ISSN: ISSN 0027-8424
PubMed: 18753625
DOI: 10.1073/PNAS.0806121105
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