Chlorine in PDB 2wcp: Crystal Structure of Mouse Cadherin-23 EC1-2

The structure of Crystal Structure of Mouse Cadherin-23 EC1-2, PDB code: 2wcp was solved by M.Sotomayor, W.Weihofen, R.Gaudet, D.P.Corey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.98
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	151.463, 151.463, 133.457, 90.00, 90.00, 120.00
R / Rfree (%)	17.3 / 18.8

The structure of Crystal Structure of Mouse Cadherin-23 EC1-2 also contains other interesting chemical elements:

Calcium	(Ca)	3 atoms
Sodium	(Na)	3 atoms

The binding sites of Chlorine atom in the Crystal Structure of Mouse Cadherin-23 EC1-2 (pdb code 2wcp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Mouse Cadherin-23 EC1-2, PDB code: 2wcp:

Chlorine binding site 1 out of 1 in the Crystal Structure of Mouse Cadherin-23 EC1-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Mouse Cadherin-23 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:43.1 occ:1.00 O A:HOH2166 2.8 31.6 1.0 N A:PHE9 3.2 16.7 1.0 CG2 A:ILE92 3.7 7.0 1.0 CA A:PHE8 3.7 16.6 1.0 CB A:PHE8 3.8 16.8 1.0 CD2 A:PHE9 3.8 18.1 1.0 CB A:PHE9 3.9 17.3 1.0 CD A:ARG94 3.9 17.1 1.0 C A:PHE8 4.0 17.0 1.0 CA A:PHE9 4.1 17.0 1.0 CG A:PHE9 4.3 17.6 1.0 O A:PHE9 4.5 16.9 1.0 NH1 A:ARG94 4.6 19.6 1.0 C A:PHE9 4.8 17.1 1.0 CG A:ARG94 4.8 15.6 1.0 CB A:ARG94 4.9 12.5 1.0 CE2 A:PHE9 4.9 18.7 1.0

M.Sotomayor, W.Weihofen, R.Gaudet, D.P.Corey. Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron V. 66 85 2010.
ISSN: ISSN 0896-6273
PubMed: 20399731
DOI: 10.1016/J.NEURON.2010.03.028