Atomistry » Chlorine » PDB 2wcg-2wj2 » 2wg3
Atomistry »
  Chlorine »
    PDB 2wcg-2wj2 »
      2wg3 »

Chlorine in PDB 2wg3: Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium

Protein crystallography data

The structure of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium, PDB code: 2wg3 was solved by B.Bishop, A.R.Aricescu, K.Harlos, C.A.O'callaghan, E.Y.Jones, C.Siebold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.60
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 102.821, 110.701, 144.381, 90.00, 90.00, 90.00
R / Rfree (%) 22.4 / 28.1

Other elements in 2wg3:

The structure of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium (pdb code 2wg3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium, PDB code: 2wg3:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 2wg3

Go back to Chlorine Binding Sites List in 2wg3
Chlorine binding site 1 out of 6 in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1200

b:59.1
occ:1.00
CG A:GLU72 3.5 21.3 1.0
N A:GLU72 3.6 18.2 1.0
CB A:GLU72 4.0 19.1 1.0
CA A:SER71 4.4 17.4 1.0
CA A:GLU72 4.4 18.9 1.0
CE1 B:TYR81 4.4 22.1 1.0
C A:SER71 4.4 17.7 1.0
CB A:SER71 4.5 17.3 1.0
CD1 B:TYR81 4.6 21.5 1.0
CD A:GLU72 4.9 24.4 1.0
NH2 B:ARG97 4.9 22.3 1.0

Chlorine binding site 2 out of 6 in 2wg3

Go back to Chlorine Binding Sites List in 2wg3
Chlorine binding site 2 out of 6 in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1642

b:50.8
occ:1.00
N C:VAL496 3.6 17.4 1.0
NH1 C:ARG434 3.6 29.2 1.0
NH2 C:ARG434 3.7 29.7 1.0
N C:VAL437 3.7 28.4 1.0
O C:VAL437 3.9 29.2 1.0
O C:VAL496 4.0 17.6 1.0
CB C:PHE495 4.1 17.8 1.0
CA C:PHE495 4.1 17.9 1.0
CZ C:ARG434 4.1 29.6 1.0
OE2 C:GLU556 4.4 30.8 1.0
C C:PHE495 4.4 17.6 1.0
CA C:VAL437 4.4 28.7 1.0
CB C:VAL437 4.5 28.6 1.0
C C:VAL437 4.5 29.0 1.0
CA C:VAL496 4.5 17.3 1.0
CA C:ALA436 4.5 27.2 1.0
CB C:VAL496 4.5 17.3 1.0
CG2 C:VAL437 4.5 28.9 1.0
CG2 C:VAL496 4.6 17.2 1.0
C C:ALA436 4.6 27.7 1.0
C C:VAL496 4.7 17.4 1.0

Chlorine binding site 3 out of 6 in 2wg3

Go back to Chlorine Binding Sites List in 2wg3
Chlorine binding site 3 out of 6 in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1643

b:54.5
occ:1.00
NE2 C:GLN420 3.8 24.7 1.0
CE1 C:HIS414 3.9 20.6 1.0
NE2 C:HIS414 3.9 21.5 1.0
N C:GLU477 4.0 28.7 1.0
OE1 C:GLU477 4.2 21.8 1.0
CB C:GLU477 4.4 27.6 1.0
CD C:GLU477 4.4 23.6 1.0
CG C:GLU477 4.5 26.0 1.0
CB C:SER476 4.6 30.2 1.0
CA C:SER476 4.7 30.0 1.0
CA C:GLU477 4.8 28.3 1.0
C C:SER476 4.9 29.4 1.0
CD C:GLN420 4.9 23.3 1.0
OE2 C:GLU477 5.0 19.4 1.0

Chlorine binding site 4 out of 6 in 2wg3

Go back to Chlorine Binding Sites List in 2wg3
Chlorine binding site 4 out of 6 in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1641

b:60.7
occ:1.00
O D:VAL326 3.3 16.0 1.0
OD2 D:ASP335 3.5 19.1 1.0
N D:ARG328 3.6 15.5 1.0
CA D:SER327 3.9 15.0 1.0
CB D:ASP335 4.1 17.5 1.0
CG2 D:THR338 4.1 16.3 1.0
C D:SER327 4.1 15.0 1.0
C D:VAL326 4.2 15.5 1.0
CG D:ASP335 4.2 18.2 1.0
CG D:ARG328 4.3 17.6 1.0
CG2 D:THR325 4.3 15.9 1.0
CB D:ARG328 4.4 15.9 1.0
N D:SER327 4.5 15.4 1.0
CA D:ARG328 4.6 15.8 1.0
CD D:ARG328 4.7 19.1 1.0
O D:THR325 4.7 16.2 1.0
CB D:THR325 4.7 16.1 1.0
CB D:SER327 4.9 14.8 1.0

Chlorine binding site 5 out of 6 in 2wg3

Go back to Chlorine Binding Sites List in 2wg3
Chlorine binding site 5 out of 6 in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1642

b:60.3
occ:1.00
OG D:SER224 3.3 18.1 1.0
NZ D:LYS578 3.3 18.4 1.0
OE2 D:GLU221 3.4 23.7 1.0
CB D:SER224 3.7 17.4 1.0
CE D:LYS578 4.4 17.3 1.0
CD D:GLU221 4.4 22.9 1.0
ND2 D:ASN576 4.6 12.0 1.0
OE1 D:GLU221 4.6 24.4 1.0
OD1 D:ASN576 4.7 13.2 1.0

Chlorine binding site 6 out of 6 in 2wg3

Go back to Chlorine Binding Sites List in 2wg3
Chlorine binding site 6 out of 6 in the Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of the Complex Between Human Hedgehog- Interacting Protein Hip and Desert Hedgehog Without Calcium within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1643

b:71.2
occ:1.00
CG D:GLU532 3.7 22.9 1.0
CD D:GLU532 4.0 26.3 1.0
C D:LYS533 4.1 21.2 1.0
N D:PRO534 4.1 21.0 1.0
CB D:SER487 4.2 29.0 1.0
OE1 D:GLU532 4.3 28.6 1.0
CA D:LYS533 4.4 21.2 1.0
OG D:SER487 4.4 29.6 1.0
CG D:PRO534 4.4 21.1 1.0
CD D:PRO534 4.4 21.1 1.0
O D:LYS533 4.4 21.6 1.0
CA D:PRO534 4.6 20.7 1.0
OE2 D:GLU532 4.6 28.2 1.0
N D:LYS533 4.7 20.8 1.0
C D:GLU532 4.8 20.5 1.0
O D:GLU532 4.8 20.1 1.0
CB D:PRO534 4.8 20.6 1.0
CB D:GLU532 4.9 20.8 1.0
CB D:LEU519 5.0 16.5 1.0

Reference:

B.Bishop, A.R.Aricescu, K.Harlos, C.A.O'callaghan, E.Y.Jones, C.Siebold. Structural Insights Into Hedgehog Ligand Sequestration By the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol. V. 16 698 2009.
ISSN: ISSN 1545-9993
PubMed: 19561611
DOI: 10.1038/NSMB.1607
Page generated: Fri Jul 11 01:22:15 2025

Last articles

Zn in 9UUO
Zn in 9UUS
Zn in 9W4R
Zn in 9VKW
Zn in 9W4S
Zn in 9VH1
Zn in 9RMX
Zn in 9RMU
Zn in 9QWN
Zn in 9U9Y
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy