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Atomistry » Chlorine » PDB 2wps-2wzc » 2wtw | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2wps-2wzc » 2wtw » |
Chlorine in PDB 2wtw: Aurora-A Inhibitor Structure (2ND Crystal Form)Enzymatic activity of Aurora-A Inhibitor Structure (2ND Crystal Form)
All present enzymatic activity of Aurora-A Inhibitor Structure (2ND Crystal Form):
2.7.11.1; Protein crystallography data
The structure of Aurora-A Inhibitor Structure (2ND Crystal Form), PDB code: 2wtw
was solved by
M.Kosmopoulou,
R.Bayliss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2wtw:
The structure of Aurora-A Inhibitor Structure (2ND Crystal Form) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Aurora-A Inhibitor Structure (2ND Crystal Form)
(pdb code 2wtw). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Aurora-A Inhibitor Structure (2ND Crystal Form), PDB code: 2wtw: Chlorine binding site 1 out of 1 in 2wtwGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Aurora-A Inhibitor Structure (2ND Crystal Form)
![]() Mono view ![]() Stereo pair view
Reference:
C.A.Dodson,
M.Kosmopoulou,
M.W.Richards,
B.Atrash,
V.Bavetsias,
J.Blagg,
R.Bayliss.
Crystal Structure of An Aurora-A Mutant That Mimics Aurora-B Bound to MLN8054: Insights Into Selectivity and Drug Design. Biochem.J. V. 427 19 2010.
Page generated: Fri Jul 11 01:41:10 2025
ISSN: ISSN 0264-6021 PubMed: 20067443 DOI: 10.1042/BJ20091530 |
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