Chlorine in PDB 2xex: Crystal Structure of Staphylococcus Aureus Elongation Factor G

The structure of Crystal Structure of Staphylococcus Aureus Elongation Factor G, PDB code: 2xex was solved by Y.Chen, R.K.Koripella, S.Sanyal, M.Selmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.20 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	47.160, 137.340, 125.360, 90.00, 94.93, 90.00
R / Rfree (%)	18.7 / 22.4

The structure of Crystal Structure of Staphylococcus Aureus Elongation Factor G also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of Staphylococcus Aureus Elongation Factor G (pdb code 2xex). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Staphylococcus Aureus Elongation Factor G, PDB code: 2xex:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Staphylococcus Aureus Elongation Factor G


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Staphylococcus Aureus Elongation Factor G within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1693 b:33.4 occ:1.00 OH A:TYR186 3.1 19.4 1.0 N A:LEU269 3.3 17.9 1.0 N A:GLN268 3.5 18.8 1.0 N A:GLY266 3.5 17.3 1.0 CA A:GLY266 3.5 16.6 1.0 CB A:GLN268 3.5 20.2 1.0 C A:GLY266 3.7 17.5 1.0 N A:VAL267 3.8 17.7 1.0 CE1 A:TYR186 3.8 16.9 1.0 CA A:GLN268 3.8 20.1 1.0 CG A:LEU269 3.9 18.0 1.0 CZ A:TYR186 3.9 18.4 1.0 C A:GLN268 4.0 19.0 1.0 CB A:LEU269 4.2 16.9 1.0 CG A:GLN268 4.3 22.8 1.0 O A:GLY266 4.4 15.0 1.0 CA A:LEU269 4.4 17.8 1.0 CD1 A:LEU269 4.4 17.6 1.0 C A:VAL267 4.5 19.9 1.0 CD1 A:ILE194 4.5 22.8 1.0 C A:LYS265 4.7 18.0 1.0 CA A:VAL267 4.8 19.5 1.0 CD A:GLN268 4.8 29.0 1.0 NE2 A:GLN268 4.9 28.6 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Staphylococcus Aureus Elongation Factor G


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Staphylococcus Aureus Elongation Factor G within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1693 b:24.3 occ:1.00 OH B:TYR186 3.1 12.8 1.0 N B:GLY266 3.3 14.2 1.0 N B:GLN268 3.4 14.9 1.0 CA B:GLY266 3.4 13.1 1.0 N B:LEU269 3.4 15.6 1.0 CB B:GLN268 3.6 16.3 1.0 C B:GLY266 3.6 15.2 1.0 O B:HOH2109 3.7 24.1 1.0 CE1 B:TYR186 3.7 16.8 1.0 N B:VAL267 3.7 15.6 1.0 CA B:GLN268 3.8 16.3 1.0 CZ B:TYR186 3.9 17.9 1.0 CG B:LEU269 3.9 15.8 1.0 C B:GLN268 4.1 15.0 1.0 O B:HOH2110 4.2 39.6 1.0 CG B:GLN268 4.3 18.6 1.0 CB B:LEU269 4.3 16.3 1.0 O B:GLY266 4.3 15.2 1.0 C B:VAL267 4.4 15.8 1.0 CD1 B:LEU269 4.4 20.4 1.0 CD1 B:ILE194 4.5 17.8 1.0 CA B:LEU269 4.5 15.8 1.0 C B:LYS265 4.5 13.8 1.0 CA B:VAL267 4.7 15.6 1.0 CD2 B:LEU269 5.0 19.4 1.0 CD B:GLN268 5.0 22.7 1.0 O B:HOH2112 5.0 31.8 1.0

Y.Chen, R.K.Koripella, S.Sanyal, M.Selmer. Staphylococcus Aureus Elongation Factor G - Structure and Analysis of A Target For Fusidic Acid. Febs J. V. 277 3789 2010.
ISSN: ISSN 1742-464X
PubMed: 20718859
DOI: 10.1111/J.1742-4658.2010.07780.X