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Atomistry » Chlorine » PDB 2xev-2xmc » 2xhr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2xev-2xmc » 2xhr » |
Chlorine in PDB 2xhr: Structure of HSP90 with Small Molecule Inhibitor BoundProtein crystallography data
The structure of Structure of HSP90 with Small Molecule Inhibitor Bound, PDB code: 2xhr
was solved by
C.W.Murray,
M.G.Carr,
O.Callaghan,
G.Chessari,
M.Congreve,
S.Cowan,
J.E.Coyle,
R.Downham,
E.Figueroa,
M.Frederickson,
B.Graham,
R.Mcmenamin,
M.A.Obrien,
S.Patel,
T.R.Phillips,
G.Williams,
A.J.Woodhead,
A.J.A.Woolford,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of HSP90 with Small Molecule Inhibitor Bound
(pdb code 2xhr). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of HSP90 with Small Molecule Inhibitor Bound, PDB code: 2xhr: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 2xhrGo back to![]() ![]()
Chlorine binding site 1 out
of 3 in the Structure of HSP90 with Small Molecule Inhibitor Bound
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 3 in 2xhrGo back to![]() ![]()
Chlorine binding site 2 out
of 3 in the Structure of HSP90 with Small Molecule Inhibitor Bound
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 3 in 2xhrGo back to![]() ![]()
Chlorine binding site 3 out
of 3 in the Structure of HSP90 with Small Molecule Inhibitor Bound
![]() Mono view ![]() Stereo pair view
Reference:
C.W.Murray,
M.G.Carr,
O.Callaghan,
G.Chessari,
M.Congreve,
S.Cowan,
J.E.Coyle,
R.Downham,
E.Figueroa,
M.Frederickson,
B.Graham,
R.Mcmenamin,
M.A.O'brien,
S.Patel,
T.R.Phillips,
G.Williams,
A.J.Woodhead,
A.J.A.Woolford.
Fragment-Based Drug Discovery Applied to HSP90. Discovery of Two Lead Series with High Ligand Efficiency. J.Med.Chem. V. 53 5942 2010.
Page generated: Fri Jul 11 01:57:45 2025
ISSN: ISSN 0022-2623 PubMed: 20718493 DOI: 10.1021/JM100059D |
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