Chlorine in PDB 2xxw: Crystal Structure of the GLUK2 (GLUR6) D776K Lbd Dimer in Complex with Glutamate

The structure of Crystal Structure of the GLUK2 (GLUR6) D776K Lbd Dimer in Complex with Glutamate, PDB code: 2xxw was solved by N.Nayeem, O.Mayans, T.Green, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.97 / 2.30
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	93.687, 106.821, 112.854, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 24.4

The binding sites of Chlorine atom in the Crystal Structure of the GLUK2 (GLUR6) D776K Lbd Dimer in Complex with Glutamate (pdb code 2xxw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the GLUK2 (GLUR6) D776K Lbd Dimer in Complex with Glutamate, PDB code: 2xxw:

Chlorine binding site 1 out of 1 in the Crystal Structure of the GLUK2 (GLUR6) D776K Lbd Dimer in Complex with Glutamate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the GLUK2 (GLUR6) D776K Lbd Dimer in Complex with Glutamate within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl901 b:21.8 occ:0.56 NH1 B:ARG775 2.9 48.7 1.0 O A:HOH2031 3.2 32.9 1.0 OG1 B:THR779 3.3 32.4 1.0 NZ B:LYS531 3.3 38.4 1.0 CD B:ARG775 3.5 44.5 1.0 CB B:THR779 3.9 30.7 1.0 CG2 B:THR779 3.9 32.8 1.0 CZ B:ARG775 4.0 49.7 1.0 NE B:ARG775 4.2 47.8 1.0 CG B:LYS531 4.3 34.6 1.0 OE1 A:GLU524 4.5 38.2 1.0 OE2 A:GLU524 4.5 41.7 1.0 CE B:LYS531 4.5 36.7 1.0 O A:PHE529 4.6 32.6 1.0 CD B:LYS531 4.6 35.4 1.0 CG B:ARG775 4.7 43.6 1.0 O B:ARG775 4.7 39.4 1.0 CA B:LYS776 4.8 47.1 1.0 O B:PHE529 4.8 30.3 1.0 CD B:LYS776 4.8 51.5 1.0 N B:LYS531 4.9 27.9 1.0 CD A:GLU524 4.9 40.4 1.0

N.Nayeem, O.Mayans, T.Green. Conformational Flexibility of the Ligand-Binding Domain Dimer in Kainate Receptor Gating and Desensitization J.Neurosci. V. 31 2916 2011.
ISSN: ISSN 0270-6474
PubMed: 21414913
DOI: 10.1523/JNEUROSCI.4771-10.2011