Chlorine in PDB 2y08: Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml

The structure of Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml, PDB code: 2y08 was solved by J.C.Carlson, S.Li, S.S.Gunatilleke, Y.Anzai, D.A.Burr, L.M.Podust, D.H.Sherman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	134.59 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	64.378, 129.558, 134.585, 90.00, 90.00, 90.00
R / Rfree (%)	14.1 / 20.5

The structure of Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml (pdb code 2y08). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml, PDB code: 2y08:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1502 b:26.5 occ:1.00 O A:HOH2230 3.1 30.9 1.0 N A:ALA38 3.1 16.1 1.0 NH1 A:ARG197 3.2 17.0 1.0 NH2 A:ARG197 3.5 17.8 1.0 O A:HOH2080 3.5 40.2 1.0 CA A:SER37 3.7 16.0 1.0 CZ A:ARG197 3.8 16.4 1.0 C A:SER37 3.9 16.5 1.0 CB A:SER37 4.0 16.4 1.0 O A:HOH2082 4.0 21.3 1.0 CG1 A:VAL196 4.0 14.5 1.0 CB A:ALA38 4.0 17.1 1.0 CA A:ALA38 4.2 16.4 1.0 OE2 A:GLU154 4.7 25.5 1.0 CD2 A:LEU82 4.7 18.0 1.0 O A:HOH2035 4.9 41.3 1.0 N A:SER37 5.0 17.9 1.0

Chlorine binding site 2 out of 2 in the Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Substrate-Free Fad-Dependent Tirandamycin Oxidase Taml within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1503 b:26.0 occ:1.00 O A:HOH2210 2.9 23.7 1.0 O A:HOH2380 2.9 28.9 1.0 N A:ASP124 3.2 12.6 1.0 CD A:PRO123 3.3 13.8 1.0 O A:HOH2199 3.4 41.1 1.0 OD2 A:ASP124 3.4 28.9 1.0 CB A:ASP124 3.5 15.1 1.0 N A:PRO123 3.5 14.4 1.0 CG A:ASP124 3.6 18.5 1.0 CB A:CYS122 3.7 16.0 1.0 C A:CYS122 3.8 14.7 1.0 CA A:CYS122 3.9 15.7 1.0 CA A:ASP124 3.9 14.1 1.0 CG A:PRO123 4.2 18.6 1.0 C A:PRO123 4.2 12.8 1.0 C7M A:FAD600 4.2 16.2 1.0 CA A:PRO123 4.3 14.1 1.0 OD1 A:ASP124 4.4 20.8 1.0 O A:CYS122 4.5 14.5 1.0 CA A:GLY331 4.6 27.7 1.0 SG A:CYS122 4.6 17.1 1.0 CB A:PRO123 4.6 14.9 1.0 O A:ALA328 4.7 21.6 1.0 MG A:MG700 4.7 31.8 1.0 C A:ASP124 4.8 13.0 1.0 N A:VAL125 4.8 13.0 1.0 CE1 A:HIS62 4.8 12.7 1.0 NE2 A:HIS62 5.0 12.6 1.0 O A:HOH2121 5.0 21.4 1.0

J.C.Carlson, S.Li, S.S.Gunatilleke, Y.Anzai, D.A.Burr, L.M.Podust, D.H.Sherman. Tirandamycin Biosynthesis Is Mediated By Co-Dependent Oxidative Enzymes Nat.Chem V. 3 628 2011.
ISSN: ISSN 1755-4330
PubMed: 21778983
DOI: 10.1038/NCHEM.1087