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Chlorine in PDB 2ylm: Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase.

Enzymatic activity of Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase.

All present enzymatic activity of Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase.:
3.4.19.12;

Protein crystallography data

The structure of Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase., PDB code: 2ylm was solved by A.C.Faesen, A.Perrakis, T.K.Sixma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.78 / 2.70
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 79.980, 82.310, 150.630, 90.00, 90.00, 90.00
R / Rfree (%) 19.1 / 21.61

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase. (pdb code 2ylm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase., PDB code: 2ylm:

Chlorine binding site 1 out of 1 in 2ylm

Go back to Chlorine Binding Sites List in 2ylm
Chlorine binding site 1 out of 1 in the Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Mechanism of USP7 (Hausp) Activation By Its C-Terminal Ubiquitin-Like Domain (Hubl) and Allosteric Regulation By Gmp-Synthetase. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1090

b:98.6
occ:1.00
NH1 A:ARG862 3.1 0.3 1.0
ND1 A:HIS792 3.2 68.6 1.0
OD1 A:ASN815 3.4 80.8 1.0
CB A:ASN815 3.8 63.1 1.0
CG A:ASN815 3.9 79.5 1.0
O A:TYR791 3.9 62.2 1.0
CA A:HIS792 3.9 61.5 1.0
CE1 A:HIS792 4.0 67.2 1.0
CE2 A:TYR791 4.2 62.8 1.0
CG A:HIS792 4.2 65.2 1.0
CD2 A:TYR791 4.4 60.3 1.0
CZ A:ARG862 4.4 0.7 1.0
CB A:HIS792 4.4 62.9 1.0
C A:TYR791 4.6 60.9 1.0
N A:HIS792 4.6 58.4 1.0
O A:HIS792 4.8 71.2 1.0
C A:HIS792 4.8 69.2 1.0
CZ A:TYR791 4.8 69.8 1.0
CD A:ARG862 4.8 90.3 1.0

Reference:

A.C.Faesen, A.M.G.Dirac, A.Shanmugham, H.Ovaa, A.Perrakis, T.K.Sixma. Mechanism of USP7/Hausp Activation By Its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation By Gmp-Synthetase Mol.Cell V. 44 147 2011.
ISSN: ISSN 1097-2765
PubMed: 21981925
DOI: 10.1016/J.MOLCEL.2011.06.034
Page generated: Fri Jul 11 02:41:49 2025

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