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Atomistry » Chlorine » PDB 3c4x-3ccm » 3c6t | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3c4x-3ccm » 3c6t » |
Chlorine in PDB 3c6t: Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14Enzymatic activity of Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14
All present enzymatic activity of Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14:
2.7.7.49; 2.7.7.7; Protein crystallography data
The structure of Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14, PDB code: 3c6t
was solved by
Y.Yan,
S.Prasad,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14
(pdb code 3c6t). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14, PDB code: 3c6t: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 3c6tGo back to![]() ![]()
Chlorine binding site 1 out
of 3 in the Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 3 in 3c6tGo back to![]() ![]()
Chlorine binding site 2 out
of 3 in the Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 3 in 3c6tGo back to![]() ![]()
Chlorine binding site 3 out
of 3 in the Crystal Structure of Hiv Reverse Transcriptase in Complex with Inhibitor 14
![]() Mono view ![]() Stereo pair view
Reference:
T.J.Tucker,
S.Saggar,
J.T.Sisko,
R.M.Tynebor,
T.M.Williams,
P.J.Felock,
J.A.Flynn,
M.T.Lai,
Y.Liang,
G.Mcgaughey,
M.Liu,
M.Miller,
G.Moyer,
V.Munshi,
R.Perlow-Poehnelt,
S.Prasad,
R.Sanchez,
M.Torrent,
J.P.Vacca,
B.L.Wan,
Y.Yan.
The Design and Synthesis of Diaryl Ether Second Generation Hiv-1 Non-Nucleoside Reverse Transcriptase Inhibitors (Nnrtis) with Enhanced Potency Versus Key Clinical Mutations. Bioorg.Med.Chem.Lett. V. 18 2959 2008.
Page generated: Sat Jul 20 16:53:16 2024
ISSN: ISSN 0960-894X PubMed: 18396399 DOI: 10.1016/J.BMCL.2008.03.064 |
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