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Atomistry » Chlorine » PDB 3dgq-3dn8 » 3dkg » |
Chlorine in PDB 3dkg: Structure of Mutant(Y1248L) Met Receptor Tyrosine Kinase in Complex with Inhibitor Sgx-523Protein crystallography data
The structure of Structure of Mutant(Y1248L) Met Receptor Tyrosine Kinase in Complex with Inhibitor Sgx-523, PDB code: 3dkg
was solved by
J.Hendle,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Mutant(Y1248L) Met Receptor Tyrosine Kinase in Complex with Inhibitor Sgx-523
(pdb code 3dkg). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Mutant(Y1248L) Met Receptor Tyrosine Kinase in Complex with Inhibitor Sgx-523, PDB code: 3dkg: Chlorine binding site 1 out of 1 in 3dkgGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Structure of Mutant(Y1248L) Met Receptor Tyrosine Kinase in Complex with Inhibitor Sgx-523
![]() Mono view ![]() Stereo pair view
Reference:
S.G.Buchanan,
J.Hendle,
P.S.Lee,
C.R.Smith,
P.Y.Bounaud,
K.A.Jessen,
C.M.Tang,
N.H.Huser,
J.D.Felce,
K.J.Froning,
M.C.Peterman,
B.E.Aubol,
S.F.Gessert,
J.M.Sauder,
K.D.Schwinn,
M.Russell,
I.A.Rooney,
J.Adams,
B.C.Leon,
T.H.Do,
J.M.Blaney,
P.A.Sprengeler,
D.A.Thompson,
L.Smyth,
L.A.Pelletier,
S.Atwell,
K.Holme,
S.R.Wasserman,
S.Emtage,
S.K.Burley,
S.H.Reich.
SGX523 Is An Exquisitely Selective, Atp-Competitive Inhibitor of the Met Receptor Tyrosine Kinase with Antitumor Activity in Vivo. Mol.Cancer Ther. V. 8 3181 2009.
Page generated: Fri Jul 11 04:32:02 2025
ISSN: ISSN 1535-7163 PubMed: 19934279 DOI: 10.1158/1535-7163.MCT-09-0477 |
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