Atomistry » Chlorine » PDB 3dgq-3dn8 » 3dlg
Atomistry »
  Chlorine »
    PDB 3dgq-3dn8 »
      3dlg »

Chlorine in PDB 3dlg: Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511.

Enzymatic activity of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511.

All present enzymatic activity of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511.:
2.7.7.49; 2.7.7.7; 3.1.26.4;

Protein crystallography data

The structure of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511., PDB code: 3dlg was solved by J.Ren, P.P.Chamberlain, D.K.Stammers, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.43 / 2.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 137.220, 109.520, 72.180, 90.00, 90.00, 90.00
R / Rfree (%) 22 / 29.9

Other elements in 3dlg:

The structure of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511. also contains other interesting chemical elements:

Fluorine (F) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511. (pdb code 3dlg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511., PDB code: 3dlg:

Chlorine binding site 1 out of 1 in 3dlg

Go back to Chlorine Binding Sites List in 3dlg
Chlorine binding site 1 out of 1 in the Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Hiv-1 Reverse Transcriptase in Complex with GW564511. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl999

b:39.5
occ:1.00
 CL1 A:GWE999 0.0 39.5 1.0
C4 A:GWE999 1.7 31.4 1.0
C5 A:GWE999 2.7 43.6 1.0
C3 A:GWE999 2.8 39.2 1.0
O A:TYR188 3.2 38.1 1.0
N A:GLY190 3.4 35.2 1.0
CD1 A:TYR181 3.5 37.1 1.0
C A:TYR188 3.6 38.5 1.0
O A:VAL179 3.6 56.1 1.0
CE1 A:TYR181 3.7 45.8 1.0
CG2 A:VAL179 3.8 37.9 1.0
C A:VAL189 3.9 38.8 1.0
CA A:GLY190 3.9 32.5 1.0
CG A:TYR181 3.9 35.5 1.0
CB A:TYR188 4.0 41.0 1.0
N A:VAL189 4.0 37.1 1.0
C2 A:GWE999 4.0 29.1 1.0
C6 A:GWE999 4.1 31.7 1.0
CA A:VAL189 4.1 28.4 1.0
CZ A:TYR181 4.2 45.2 1.0
CD2 A:TYR181 4.4 39.3 1.0
CA A:TYR188 4.4 35.6 1.0
C A:VAL179 4.5 48.6 1.0
N A:TYR181 4.5 43.5 1.0
CB A:TYR181 4.6 34.4 1.0
CE2 A:TYR181 4.6 43.8 1.0
C1 A:GWE999 4.6 25.5 1.0
CG1 A:VAL106 4.6 30.4 1.0
CG2 A:VAL106 4.6 26.5 1.0
O A:VAL189 4.7 44.2 1.0
CB A:VAL179 5.0 50.6 1.0
OH A:TYR181 5.0 54.8 1.0
C A:GLY190 5.0 34.9 1.0

Reference:

J.Ren, P.P.Chamberlain, A.Stamp, S.A.Short, K.L.Weaver, K.R.Romines, R.Hazen, A.Freeman, R.G.Ferris, C.W.Andrews, L.Boone, J.H.Chan, D.K.Stammers. Structural Basis For the Improved Drug Resistance Profile of New Generation Benzophenone Non-Nucleoside Hiv-1 Reverse Transcriptase Inhibitors. J.Med.Chem. V. 51 5000 2008.
ISSN: ISSN 0022-2623
PubMed: 18665583
DOI: 10.1021/JM8004493
Page generated: Fri Jul 11 04:32:50 2025

Last articles

Mg in 1S8F
Mg in 1S83
Mg in 1S77
Mg in 1S76
Mg in 1S4E
Mg in 1S6P
Mg in 1S6H
Mg in 1S5J
Mg in 1S5G
Mg in 1S2V
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy