Atomistry » Chlorine » PDB 3dna-3dzc » 3drc
Atomistry »
  Chlorine »
    PDB 3dna-3dzc »
      3drc »

Chlorine in PDB 3drc: Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis

Enzymatic activity of Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis

All present enzymatic activity of Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis:
1.5.1.3;

Protein crystallography data

The structure of Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis, PDB code: 3drc was solved by S.J.Oatley, J.Kraut, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 1.90
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 93.120, 93.120, 73.870, 90.00, 90.00, 120.00
R / Rfree (%) n/a / n/a

Other elements in 3drc:

The structure of Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis (pdb code 3drc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis, PDB code: 3drc:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 3drc

Go back to Chlorine Binding Sites List in 3drc
Chlorine binding site 1 out of 2 in the Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl401

b:23.0
occ:1.00
 O A:HOH580 3.0 77.0 1.0
O A:HOH460 3.1 38.0 1.0
N A:GLY96 3.2 12.0 1.0
N A:THR46 3.3 11.0 1.0
OG1 A:THR46 3.4 16.0 1.0
N A:HIS45 3.4 14.0 1.0
CA A:GLY43 3.5 17.0 1.0
C A:GLY43 3.5 19.0 1.0
CB A:HIS45 3.5 13.0 1.0
O A:HOH436 3.7 37.0 1.0
CA A:GLY96 3.7 11.0 1.0
O A:GLY43 3.9 16.0 1.0
N A:ARG44 3.9 14.0 1.0
N A:GLY43 3.9 18.0 1.0
CA A:HIS45 3.9 13.0 1.0
CB A:THR46 4.0 14.0 1.0
C A:GLY95 4.1 16.0 1.0
O A:HOH429 4.1 48.0 1.0
C A:HIS45 4.1 14.0 1.0
ND1 A:HIS45 4.2 24.0 1.0
CA A:THR46 4.2 13.0 1.0
O A:GLY95 4.2 16.0 1.0
CG A:HIS45 4.3 18.0 1.0
O A:HOH461 4.4 38.0 1.0
C A:ARG44 4.4 16.0 1.0
C A:GLY96 4.6 18.0 1.0
CA A:ARG44 4.7 17.0 1.0
O A:HOH581 4.8 63.0 1.0
CG2 A:VAL99 5.0 20.0 1.0

Chlorine binding site 2 out of 2 in 3drc

Go back to Chlorine Binding Sites List in 3drc
Chlorine binding site 2 out of 2 in the Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl605

b:28.0
occ:1.00
 O B:HOH742 3.1 36.0 1.0
N B:THR46 3.2 24.0 1.0
OG1 B:THR46 3.2 19.0 1.0
N B:GLY96 3.3 15.0 1.0
CA B:GLY43 3.4 22.0 1.0
C B:GLY43 3.6 19.0 1.0
N B:HIS45 3.6 22.0 1.0
CB B:HIS45 3.8 33.0 1.0
O B:GLY43 3.9 21.0 1.0
CA B:GLY96 3.9 16.0 1.0
CB B:THR46 3.9 21.0 1.0
N B:GLY43 3.9 16.0 1.0
CA B:HIS45 3.9 24.0 1.0
C B:HIS45 4.1 26.0 1.0
N B:ARG44 4.1 23.0 1.0
C B:GLY95 4.1 17.0 1.0
CA B:THR46 4.1 22.0 1.0
O B:GLY95 4.1 18.0 1.0
O B:HOH741 4.4 53.0 1.0
CD2 B:HIS45 4.5 43.0 1.0
C B:ARG44 4.5 23.0 1.0
CG B:HIS45 4.6 42.0 1.0
C B:GLY96 4.8 16.0 1.0
CG2 B:VAL99 4.8 20.0 1.0
CA B:ARG44 4.9 27.0 1.0
O B:HOH635 4.9 31.0 1.0
O B:HOH695 5.0 61.0 1.0

Reference:

M.S.Warren, K.A.Brown, M.F.Farnum, E.E.Howell, J.Kraut. Investigation of the Functional Role of Tryptophan-22 in Escherichia Coli Dihydrofolate Reductase By Site-Directed Mutagenesis. Biochemistry V. 30 11092 1991.
ISSN: ISSN 0006-2960
PubMed: 1932031
DOI: 10.1021/BI00110A011
Page generated: Fri Jul 11 04:37:32 2025

Last articles

K in 4E48
K in 4E2G
K in 4E0W
K in 4E02
K in 4E01
K in 4E00
K in 4DXT
K in 4DXS
K in 4DZY
K in 4DUR
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy