Atomistry » Chlorine » PDB 3dna-3dzc » 3du0
Atomistry »
  Chlorine »
    PDB 3dna-3dzc »
      3du0 »

Chlorine in PDB 3du0: E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site

Enzymatic activity of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site

All present enzymatic activity of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site:
4.2.1.52;

Protein crystallography data

The structure of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site, PDB code: 3du0 was solved by R.C.J.Dobson, S.R.A.Devenish, J.A.Gerrard, G.B.Jameson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.14 / 2.00
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 120.950, 120.950, 110.030, 90.00, 90.00, 120.00
R / Rfree (%) 18.8 / 24.5

Other elements in 3du0:

The structure of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site also contains other interesting chemical elements:

Potassium (K) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site (pdb code 3du0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site, PDB code: 3du0:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 3du0

Go back to Chlorine Binding Sites List in 3du0
Chlorine binding site 1 out of 4 in the E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl297

b:33.8
occ:1.00
 OG A:SER137 3.1 29.4 1.0
N A:SER137 3.2 23.9 1.0
CD A:PRO136 3.4 22.6 1.0
N A:PRO136 3.4 23.8 1.0
CB A:SER137 3.6 24.2 1.0
C A:VAL135 3.6 21.8 1.0
O A:ALA163 3.7 26.3 1.0
CA A:THR164 3.8 22.4 1.0
CA A:VAL135 3.9 21.4 1.0
CG2 A:VAL135 3.9 18.8 1.0
CA A:SER137 4.0 24.2 1.0
C A:ALA163 4.1 24.8 1.0
C A:PRO136 4.2 23.1 1.0
CA A:PRO136 4.2 23.4 1.0
O A:VAL135 4.2 22.9 1.0
N A:THR164 4.2 23.5 1.0
CG A:PRO136 4.3 22.3 1.0
CB A:PRO136 4.3 24.1 1.0
O A:THR164 4.5 27.6 1.0
CG2 A:THR164 4.5 20.5 1.0
CB A:VAL135 4.5 22.0 1.0
C A:THR164 4.6 24.5 1.0
CB A:THR164 4.6 23.4 1.0
CB A:ALA163 4.9 22.1 1.0

Chlorine binding site 2 out of 4 in 3du0

Go back to Chlorine Binding Sites List in 3du0
Chlorine binding site 2 out of 4 in the E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl298

b:30.5
occ:0.50
 O A:HOH318 2.5 26.6 1.0
N A:LEU167 3.2 22.6 1.0
OD1 A:ASN166 3.5 29.2 1.0
O A:HOH392 3.7 35.0 1.0
CB A:LEU167 3.8 18.7 1.0
CA A:LEU167 3.9 20.8 1.0
C A:ASN166 4.0 21.5 1.0
N A:THR168 4.0 24.1 1.0
CA A:ASN166 4.1 21.9 1.0
CG2 A:THR168 4.2 22.1 1.0
C A:LEU167 4.4 22.7 1.0
CG A:LEU167 4.4 19.7 1.0
O A:GLY165 4.5 21.5 1.0
CG A:ASN166 4.5 25.6 1.0
CD1 A:LEU167 4.8 21.4 1.0
OG1 A:THR168 4.8 32.5 1.0
CB A:ASN166 4.9 21.8 1.0
CB A:THR168 5.0 24.6 1.0
O A:ASN166 5.0 23.0 1.0

Chlorine binding site 3 out of 4 in 3du0

Go back to Chlorine Binding Sites List in 3du0
Chlorine binding site 3 out of 4 in the E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl296

b:27.9
occ:0.50
 O B:HOH304 2.6 22.7 1.0
N B:LEU167 3.2 19.8 1.0
OD1 B:ASN166 3.7 25.8 1.0
O B:HOH389 3.7 32.0 1.0
CB B:LEU167 3.8 18.5 1.0
CA B:LEU167 4.0 19.9 1.0
C B:ASN166 4.1 19.7 1.0
CA B:ASN166 4.1 19.7 1.0
N B:THR168 4.2 21.2 1.0
CG B:LEU167 4.2 19.9 1.0
O B:GLY165 4.3 20.2 1.0
CD1 B:LEU167 4.4 14.7 1.0
CG2 B:THR168 4.4 16.3 1.0
C B:LEU167 4.6 20.3 1.0
CG B:ASN166 4.6 24.4 1.0
CB B:ASN166 4.9 20.9 1.0

Chlorine binding site 4 out of 4 in 3du0

Go back to Chlorine Binding Sites List in 3du0
Chlorine binding site 4 out of 4 in the E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of E. Coli Dihydrodipicolinate Synthase with First Substrate, Pyruvate, Bound in Active Site within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl297

b:35.6
occ:1.00
 OG B:SER137 3.1 26.6 1.0
N B:SER137 3.2 22.3 1.0
CB B:SER137 3.4 21.8 1.0
CD B:PRO136 3.4 20.9 1.0
O B:ALA163 3.4 21.6 1.0
N B:PRO136 3.5 19.8 1.0
C B:VAL135 3.7 18.5 1.0
CA B:THR164 3.8 18.9 1.0
CA B:SER137 3.9 21.6 1.0
CA B:VAL135 3.9 18.3 1.0
CG2 B:VAL135 4.0 13.9 1.0
C B:ALA163 4.0 19.6 1.0
C B:PRO136 4.2 21.1 1.0
N B:THR164 4.2 18.0 1.0
CA B:PRO136 4.3 19.1 1.0
CB B:PRO136 4.3 19.2 1.0
CG B:PRO136 4.4 17.7 1.0
O B:VAL135 4.4 17.5 1.0
O B:THR164 4.5 23.1 1.0
C B:THR164 4.5 20.2 1.0
CB B:VAL135 4.6 19.5 1.0
CG2 B:THR164 4.7 16.7 1.0
CB B:THR164 4.7 18.7 1.0

Reference:

S.R.Devenish, J.A.Gerrard, G.B.Jameson, R.C.Dobson. The High-Resolution Structure of Dihydrodipicolinate Synthase From Escherichia Coli Bound to Its First Substrate, Pyruvate. Acta Crystallogr.,Sect.F V. 64 1092 2008.
ISSN: ESSN 1744-3091
PubMed: 19052357
DOI: 10.1107/S1744309108033654
Page generated: Fri Jul 11 04:38:43 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy