Chlorine in PDB 3dzu: Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide

The structure of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide, PDB code: 3dzu was solved by V.Chandra, P.Huang, Y.Hamuro, S.Raghuram, Y.Wang, T.P.Burris, F.Rastinejad, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.93 / 3.20
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	64.186, 66.907, 78.464, 70.95, 82.56, 62.88
R / Rfree (%)	20.1 / 27.2

The structure of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide (pdb code 3dzu). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide, PDB code: 3dzu:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl701 b:74.0 occ:1.00 CL20 D:PLB701 0.0 74.0 1.0 C16 D:PLB701 1.7 74.1 1.0 C15 D:PLB701 2.7 74.4 1.0 C17 D:PLB701 2.8 71.4 1.0 CB D:MET329 4.0 0.7 1.0 C14 D:PLB701 4.1 76.0 1.0 CD1 D:ILE326 4.1 63.4 1.0 C18 D:PLB701 4.1 71.9 1.0 CB D:ALA292 4.2 36.4 1.0 CG2 D:ILE326 4.4 62.8 1.0 N D:LEU330 4.5 49.3 1.0 CB D:LEU330 4.6 40.3 1.0 C13 D:PLB701 4.6 74.2 1.0 O D:ILE326 4.7 52.8 1.0 CG D:MET329 4.8 0.6 1.0 CA D:LEU330 4.8 48.4 1.0 CA D:ILE326 4.9 52.4 1.0

Chlorine binding site 2 out of 2 in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with Bvt.13, 9-Cis Retinoic Acid and NCOA2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl701 b:75.7 occ:1.00 CL19 D:PLB701 0.0 75.7 1.0 C14 D:PLB701 1.7 76.0 1.0 C15 D:PLB701 2.7 74.4 1.0 C13 D:PLB701 2.8 74.2 1.0 N10 D:PLB701 3.1 71.8 1.0 O D:LEU340 3.2 62.3 1.0 C11 D:PLB701 3.2 72.5 1.0 CD1 D:LEU333 3.3 50.1 1.0 O9 D:PLB701 3.3 54.3 1.0 C2 D:PLB701 4.1 68.5 1.0 C16 D:PLB701 4.1 74.1 1.0 C18 D:PLB701 4.1 71.9 1.0 C7 D:PLB701 4.2 65.0 1.0 O12 D:PLB701 4.2 70.6 1.0 CD1 D:LEU330 4.2 39.7 1.0 C D:LEU340 4.4 61.8 1.0 CG2 D:VAL339 4.4 32.0 1.0 C1 D:PLB701 4.5 65.7 1.0 CA D:ILE341 4.6 61.4 1.0 C17 D:PLB701 4.6 71.4 1.0 CG D:LEU333 4.7 50.3 1.0 CB D:LEU333 4.8 50.8 1.0 CG2 D:ILE341 4.8 53.4 1.0 CG D:ARG288 5.0 73.5 1.0 N D:ILE341 5.0 60.4 1.0

V.Chandra, P.Huang, Y.Hamuro, S.Raghuram, Y.Wang, T.P.Burris, F.Rastinejad. Structure of the Intact Ppar-Gamma-Rxr- Nuclear Receptor Complex on Dna. Nature V. 456 350 2008.
ISSN: ISSN 0028-0836
PubMed: 19043829
DOI: 10.1038/NATURE07413