|
Atomistry » Chlorine » PDB 3hd1-3hl7 » 3heg | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3hd1-3hl7 » 3heg » |
Chlorine in PDB 3heg: P38 in Complex with SorafenibEnzymatic activity of P38 in Complex with Sorafenib
All present enzymatic activity of P38 in Complex with Sorafenib:
2.7.11.24; Protein crystallography data
The structure of P38 in Complex with Sorafenib, PDB code: 3heg
was solved by
H.V.Namboodiri,
M.Karpusas,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3heg:
The structure of P38 in Complex with Sorafenib also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the P38 in Complex with Sorafenib
(pdb code 3heg). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the P38 in Complex with Sorafenib, PDB code: 3heg: Chlorine binding site 1 out of 1 in 3hegGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the P38 in Complex with Sorafenib
![]() Mono view ![]() Stereo pair view
Reference:
H.V.Namboodiri,
M.Bukhtiyarova,
J.Ramcharan,
M.Karpusas,
Y.Lee,
E.B.Springman.
Analysis of Imatinib and Sorafenib Binding to P38ALPHA Compared with C-Abl and B-Raf Provides Structural Insights For Understanding the Selectivity of Inhibitors Targeting the Dfg-Out Form of Protein Kinases. Biochemistry V. 49 3611 2010.
Page generated: Fri Jul 11 05:56:10 2025
ISSN: ISSN 0006-2960 PubMed: 20337484 DOI: 10.1021/BI100070R |
Last articlesMn in 9LJUMn in 9LJW Mn in 9LJS Mn in 9LJR Mn in 9LJT Mn in 9LJV Mg in 9UA2 Mg in 9R96 Mg in 9VM1 Mg in 9P01 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |