Chlorine in PDB 3hlt: The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2)

The structure of The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2), PDB code: 3hlt was solved by E.Ugochukwu, N.Shafqat, W.W.Yue, R.Cocking, J.E.Bray, J.R.C.Muniz, T.Krojer, F.Von Delft, C.Bountra, C.H.Arrowsmith, J.Weigelt, A.Edwards, U.Oppermann, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.36 / 2.30
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	68.940, 77.680, 103.990, 90.00, 90.00, 90.00
R / Rfree (%)	21.3 / 26.6

The structure of The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2) also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2) (pdb code 3hlt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2), PDB code: 3hlt:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl268 b:63.1 occ:1.00 N A:GLY191 3.4 25.6 1.0 CA A:GLY191 3.8 26.1 1.0 N A:GLY193 3.9 27.6 1.0 CA A:GLY193 4.1 27.4 1.0 C A:GLY191 4.3 26.6 1.0 N A:THR192 4.5 26.6 1.0 C A:ARG190 4.6 25.3 1.0 CA A:ARG190 4.8 24.7 1.0 O A:LEU189 4.9 22.6 1.0 O A:GLY191 4.9 26.9 1.0

Chlorine binding site 2 out of 2 in the The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl268 b:46.5 occ:0.50 N C:GLY191 3.7 25.2 1.0 CA C:GLY191 4.3 25.9 1.0 N C:GLY193 4.4 27.6 1.0 CA C:ARG190 4.6 24.7 1.0 C C:ARG190 4.7 24.9 1.0 N C:THR192 4.7 27.0 1.0 CA C:GLY193 4.7 28.1 1.0 C C:GLY191 4.8 26.5 1.0 CG C:ARG190 4.9 24.7 1.0 O C:LEU189 5.0 24.9 1.0

E.Ugochukwu, N.Shafqat, W.W.Yue, R.Cocking, J.E.Bray, J.R.C.Muniz, T.Krojer, F.Von Delft, C.Bountra, C.H.Arrowsmith, J.Weigelt, A.Edwards, U.Oppermann, Structural Genomics Consortium (Sgc). The Crystal Structure of Human Haloacid Dehalogenase-Like Hydrolase Domain Containing 2 (HDHD2) To Be Published.