Chlorine in PDB 3iuy: Crystal Structure of DDX53 Dead-Box Domain

The structure of Crystal Structure of DDX53 Dead-Box Domain, PDB code: 3iuy was solved by P.Schutz, T.Karlberg, R.Collins, C.H.Arrowsmith, H.Berglund, C.Bountra, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, A.Johansson, I.Johansson, A.Kallas, P.Kraulis, T.Kotenyova, A.Kotzsch, N.Markova, M.Moche, T.K.Nielsen, P.Nordlund, T.Nyman, C.Persson, A.K.Roos, M.I.Siponen, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, E.Wahlberg, J.Weigelt, M.Welin, M.Wisniewska, H.M.Schuler, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.13 / 2.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.442, 61.251, 65.787, 90.00, 96.36, 90.00
R / Rfree (%)	20.1 / 25.1

The binding sites of Chlorine atom in the Crystal Structure of DDX53 Dead-Box Domain (pdb code 3iuy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of DDX53 Dead-Box Domain, PDB code: 3iuy:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of DDX53 Dead-Box Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of DDX53 Dead-Box Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:23.9 occ:1.00 N A:CYS214 3.3 13.7 1.0 O A:CYS214 3.5 13.0 1.0 CA A:THR213 3.6 15.4 1.0 CB A:THR213 3.8 15.5 1.0 C A:THR213 3.9 15.3 1.0 CG2 A:THR213 4.1 12.6 1.0 CA A:CYS214 4.3 13.5 1.0 C A:CYS214 4.3 13.7 1.0 O A:HOH174 4.4 19.2 1.0 O A:MET212 4.5 19.6 1.0 CB A:CYS214 4.7 13.3 1.0 N A:THR213 4.9 16.4 1.0 OD2 A:ASP215 4.9 16.6 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of DDX53 Dead-Box Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of DDX53 Dead-Box Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1 b:25.1 occ:1.00 O A:HOH69 2.9 25.2 1.0 O A:HOH28 3.1 19.6 1.0 NE B:ARG377 3.1 22.4 1.0 NH2 B:ARG377 3.3 15.8 1.0 N A:ASP433 3.5 17.2 1.0 CZ B:ARG377 3.7 21.8 1.0 CD A:PRO434 3.9 14.7 1.0 CA A:ASP433 4.0 17.0 1.0 OD1 A:ASP433 4.2 20.7 1.0 CD B:ARG377 4.2 20.1 1.0 CG B:ARG377 4.3 21.9 1.0 CB B:ARG377 4.3 21.8 1.0 NH2 B:ARG407 4.4 27.2 1.0 C A:LYS432 4.4 18.3 1.0 CA A:LYS432 4.5 19.0 1.0 O A:LEU431 4.6 19.7 1.0 CD2 A:LEU428 4.9 20.7 1.0 N A:PRO434 4.9 14.2 1.0 CG A:PRO434 4.9 14.3 1.0 CG A:LEU428 4.9 23.3 1.0 O B:ARG377 5.0 21.8 1.0 CG A:ASP433 5.0 20.3 1.0 OG A:SER219 5.0 22.2 1.0

P.Schutz, T.Karlberg, S.Van Den Berg, R.Collins, L.Lehtio, M.Hogbom, L.Holmberg-Schiavone, W.Tempel, H.W.Park, M.Hammarstrom, M.Moche, A.G.Thorsell, H.Schuler. Comparative Structural Analysis of Human Dead-Box Rna Helicases. Plos One V. 5 12791 2010.
ISSN: ESSN 1932-6203
PubMed: 20941364
DOI: 10.1371/JOURNAL.PONE.0012791