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Atomistry » Chlorine » PDB 3lcd-3lnr » 3le6 » |
Chlorine in PDB 3le6: The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine InhibitorEnzymatic activity of The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine Inhibitor
All present enzymatic activity of The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine Inhibitor:
2.7.11.22; Protein crystallography data
The structure of The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine Inhibitor, PDB code: 3le6
was solved by
C.M.Lukacs,
A.Swain,
R.L.Crowther,
R.U.Kammlott,
J.J.Liu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine Inhibitor
(pdb code 3le6). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine Inhibitor, PDB code: 3le6: Chlorine binding site 1 out of 1 in 3le6Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the The Structure of Cyclin Dependent Kinase 2 (CKD2) with A Pyrazolobenzodiazepine Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.J.Liu,
I.Daniewski,
Q.Ding,
B.Higgins,
G.Ju,
K.Kolinsky,
F.Konzelmann,
C.Lukacs,
G.Pizzolato,
P.Rossman,
A.Swain,
K.Thakkar,
C.C.Wei,
D.Miklowski,
H.Yang,
X.Yin,
P.M.Wovkulich.
Pyrazolobenzodiazepines: Part I. Synthesis and Sar of A Potent Class of Kinase Inhibitors. Bioorg.Med.Chem.Lett. V. 20 5984 2010.
Page generated: Fri Jul 11 07:27:01 2025
ISSN: ISSN 0960-894X PubMed: 20832307 DOI: 10.1016/J.BMCL.2010.08.079 |
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