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Atomistry » Chlorine » PDB 3lnz-3lz0 » 3ls8 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3lnz-3lz0 » 3ls8 » |
Chlorine in PDB 3ls8: Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-PhenolEnzymatic activity of Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol
All present enzymatic activity of Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol:
2.7.1.137; Protein crystallography data
The structure of Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol, PDB code: 3ls8
was solved by
L.Tresaugues,
M.Welin,
C.H.Arrowsmith,
H.Berglund,
C.Bountra,
R.Collins,
A.M.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
I.Johansson,
T.Karlberg,
T.Kotenyova,
P.Kraulis,
M.Moche,
T.Nyman,
C.Persson,
H.Schuler,
P.Schutz,
M.I.Siponen,
A.G.Thorsell,
S.Van Den Berg,
E.Wahlberg,
J.Weigelt,
M.Wisniewska,
P.Nordlund,
Structural Genomics Consortium(Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol
(pdb code 3ls8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol, PDB code: 3ls8: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 3ls8Go back to![]() ![]()
Chlorine binding site 1 out
of 4 in the Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 4 in 3ls8Go back to![]() ![]()
Chlorine binding site 2 out
of 4 in the Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 4 in 3ls8Go back to![]() ![]()
Chlorine binding site 3 out
of 4 in the Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol
![]() Mono view ![]() Stereo pair view
Chlorine binding site 4 out of 4 in 3ls8Go back to![]() ![]()
Chlorine binding site 4 out
of 4 in the Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4- Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]-Phenol
![]() Mono view ![]() Stereo pair view
Reference:
L.Tresaugues,
M.Welin,
C.H.Arrowsmith,
H.Berglund,
C.Bountra,
R.Collins,
A.M.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
I.Johansson,
T.Karlberg,
T.Kotenyova,
P.Kraulis,
M.Moche,
T.Nyman,
C.Persson,
H.Schuler,
P.Schutz,
M.I.Siponen,
A.G.Thorsell,
S.Van Den Berg,
E.Wahlberg,
J.Weigelt,
M.Wisniewska,
P.Nordlund.
Crystal Structure of Human PIK3C3 in Complex with 3-[4-(4-Morpholinyl)Thieno[3,2-D]Pyrimidin-2-Yl]- Phenol To Be Published.
Page generated: Sat Jul 20 23:37:33 2024
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