Chlorine »
PDB 3lz1-3m98 »
3m2n »
Chlorine in PDB 3m2n: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
Enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide, PDB code: 3m2n
was solved by
S.Grazulis,
E.Manakova,
D.Golovenko,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.78 / 1.65 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.041, 41.253, 71.858, 90.00, 104.74, 90.00 |
| R / Rfree (%) | 15.5 / 20.3 |
Other elements in 3m2n:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
(pdb code 3m2n). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide, PDB code: 3m2n:
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide, PDB code: 3m2n:
Chlorine binding site 1 out of 1 in 3m2n
Go back to
Chlorine Binding Sites List in 3m2n
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 4-{2-[N- (6-Chloro-5-Nitropyrimidin-4-Yl)Amino]Ethyl}Benzenesulfonamide within 5.0Å range:
|
Reference:
E.Capkauskaite,
A.Zubriene,
L.Baranauskiene,
G.Tamulaitiene,
E.Manakova,
V.Kairys,
S.Grazulis,
S.Tumkevicius,
D.Matulis.
Design of [(2-Pyrimidinylthio)Acetyl]Benzenesulfonamides As Inhibitors of Human Carbonic Anhydrases. Eur.J.Med.Chem. V. 51 259 2012.
ISSN: ISSN 0223-5234
PubMed: 22440859
DOI: 10.1016/J.EJMECH.2012.02.050
Page generated: Fri Jul 11 07:45:13 2025
ISSN: ISSN 0223-5234
PubMed: 22440859
DOI: 10.1016/J.EJMECH.2012.02.050
Last articles
F in 5R8DF in 5R85
F in 5R7Z
F in 5R60
F in 5R5W
F in 5R5V
F in 5R5P
F in 5R5M
F in 5R5F
F in 5R5C
