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Atomistry » Chlorine » PDB 3oox-3oxh » 3otu » |
Chlorine in PDB 3otu: PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30Enzymatic activity of PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30
All present enzymatic activity of PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30:
2.7.11.1; Protein crystallography data
The structure of PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30, PDB code: 3otu
was solved by
J.D.Sadowsky,
J.A.Wells,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30
(pdb code 3otu). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30, PDB code: 3otu: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 3otuGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 3otuGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the PDK1 Mutant Bound to Allosteric Disulfide Fragment Activator JS30
![]() Mono view ![]() Stereo pair view
Reference:
J.D.Sadowsky,
M.A.Burlingame,
D.W.Wolan,
C.L.Mcclendon,
M.P.Jacobson,
J.A.Wells.
Turning A Protein Kinase on or Off From A Single Allosteric Site Via Disulfide Trapping. Proc.Natl.Acad.Sci.Usa V. 108 6056 2011.
Page generated: Fri Jul 11 08:53:01 2025
ISSN: ISSN 0027-8424 PubMed: 21430264 DOI: 10.1073/PNAS.1102376108 |
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