Chlorine in PDB 3qw4: Structure of Leishmania Donovani Ump Synthase

All present enzymatic activity of Structure of Leishmania Donovani Ump Synthase:
2.4.2.10; 4.1.1.23;

The structure of Structure of Leishmania Donovani Ump Synthase, PDB code: 3qw4 was solved by J.B.French, S.E.Ealick, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.96 / 3.00
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	64.722, 64.722, 477.596, 90.00, 90.00, 90.00
R / Rfree (%)	23.6 / 30.4

The binding sites of Chlorine atom in the Structure of Leishmania Donovani Ump Synthase (pdb code 3qw4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Leishmania Donovani Ump Synthase, PDB code: 3qw4:

Chlorine binding site 1 out of 1 in the Structure of Leishmania Donovani Ump Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Leishmania Donovani Ump Synthase within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl453 b:73.6 occ:1.00 O C:HOH472 2.7 47.2 1.0 NH1 C:ARG346 3.2 97.3 1.0 NH2 C:ARG291 3.3 76.7 1.0 O C:HOH464 3.4 48.0 1.0 O C:HOH465 3.5 76.0 1.0 O C:HOH473 3.5 58.5 1.0 NE C:ARG291 3.7 72.3 1.0 N C:TYR324 3.7 70.1 1.0 CZ C:ARG291 3.9 73.7 1.0 N C:ALA325 3.9 67.3 1.0 CB C:TYR324 4.3 67.9 1.0 O2' C:U5P7485 4.3 86.2 1.0 CB C:ALA325 4.4 67.6 1.0 CA C:TYR324 4.4 68.3 1.0 CZ C:ARG346 4.5 98.0 1.0 O C:PRO323 4.5 73.3 1.0 C C:PRO323 4.5 71.1 1.0 C C:TYR324 4.7 67.1 1.0 CD2 C:TYR324 4.7 72.3 1.0 CA C:ALA325 4.8 66.3 1.0 CD C:ARG291 4.9 70.3 1.0 NH2 C:ARG346 5.0 100.0 1.0

J.B.French, P.A.Yates, D.R.Soysa, J.M.Boitz, N.S.Carter, B.Chang, B.Ullman, S.E.Ealick. The Leishmania Donovani Ump Synthase Is Essential For Promastigote Viability and Has An Unusual Tetrameric Structure That Exhibits Substrate-Controlled Oligomerization. J.Biol.Chem. V. 286 20930 2011.
ISSN: ISSN 0021-9258
PubMed: 21507942
DOI: 10.1074/JBC.M111.228213