Atomistry » Chlorine » PDB 3qvp-3r40 » 3qyl
Atomistry »
  Chlorine »
    PDB 3qvp-3r40 »
      3qyl »

Chlorine in PDB 3qyl: Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate

Enzymatic activity of Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate

All present enzymatic activity of Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate:
1.5.1.3;

Protein crystallography data

The structure of Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate, PDB code: 3qyl was solved by E.J.Collins, A.L.Lee, M.J.Carroll, R.V.Mauldin, A.V.Gromova, S.F.Singleton, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.02 / 1.79
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 33.865, 44.820, 97.808, 90.00, 90.00, 90.00
R / Rfree (%) 17.5 / 20.9

Other elements in 3qyl:

The structure of Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate also contains other interesting chemical elements:

Calcium (Ca) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate (pdb code 3qyl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate, PDB code: 3qyl:

Chlorine binding site 1 out of 1 in 3qyl

Go back to Chlorine Binding Sites List in 3qyl
Chlorine binding site 1 out of 1 in the Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Sensitivity of Receptor Internal Motions to Ligand Binding Affinity and Kinetic Off-Rate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl227

b:24.8
occ:1.00
 NH1 A:ARG57 3.1 14.5 1.0
NH2 A:ARG57 3.2 14.4 1.0
CE A:LYS32 3.5 43.8 1.0
CZ A:ARG57 3.6 22.6 1.0
CB A:LYS32 3.8 15.5 1.0
CD2 A:PHE31 3.8 13.1 1.0
CG A:LYS32 3.9 14.8 1.0
CE2 A:PHE31 4.0 14.4 1.0
CA A:LYS32 4.1 12.8 1.0
CD2 A:LEU54 4.2 18.1 1.0
CD A:LYS32 4.3 19.8 1.0
N A:LYS32 4.5 13.2 1.0
NZ A:LYS32 4.6 53.1 1.0
O A:LEU28 4.7 15.5 1.0
NE A:ARG57 4.9 14.7 1.0

Reference:

M.J.Carroll, R.V.Mauldin, A.V.Gromova, S.F.Singleton, E.J.Collins, A.L.Lee. Evidence For Dynamics in Proteins As A Mechanism For Ligand Dissociation. Nat.Chem.Biol. V. 8 246 2012.
ISSN: ISSN 1552-4450
PubMed: 22246400
DOI: 10.1038/NCHEMBIO.769
Page generated: Sun Jul 21 03:17:49 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy