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Atomistry » Chlorine » PDB 3rv4-3s8n » 3s00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3rv4-3s8n » 3s00 » |
Chlorine in PDB 3s00: CDK2 in Complex with Inhibitor L4-14Enzymatic activity of CDK2 in Complex with Inhibitor L4-14
All present enzymatic activity of CDK2 in Complex with Inhibitor L4-14:
2.7.11.22; Protein crystallography data
The structure of CDK2 in Complex with Inhibitor L4-14, PDB code: 3s00
was solved by
S.Betzi,
R.Alam,
H.Han,
A.Becker,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the CDK2 in Complex with Inhibitor L4-14
(pdb code 3s00). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the CDK2 in Complex with Inhibitor L4-14, PDB code: 3s00: Chlorine binding site 1 out of 1 in 3s00Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the CDK2 in Complex with Inhibitor L4-14
![]() Mono view ![]() Stereo pair view
Reference:
E.Schonbrunn,
S.Betzi,
R.Alam,
M.P.Martin,
A.Becker,
H.Han,
R.Francis,
R.Chakrasali,
S.Jakkaraj,
A.Kazi,
S.M.Sebti,
C.L.Cubitt,
A.W.Gebhard,
L.A.Hazlehurst,
J.S.Tash,
G.I.Georg.
Development of Highly Potent and Selective Diaminothiazole Inhibitors of Cyclin-Dependent Kinases. J.Med.Chem. V. 56 3768 2013.
Page generated: Fri Jul 11 10:04:28 2025
ISSN: ISSN 0022-2623 PubMed: 23600925 DOI: 10.1021/JM301234K |
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