Atomistry » Chlorine » PDB 3rv4-3s8n » 3s1y
Atomistry »
  Chlorine »
    PDB 3rv4-3s8n »
      3s1y »

Chlorine in PDB 3s1y: Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor

Enzymatic activity of Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor

All present enzymatic activity of Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor:
3.5.2.6;

Protein crystallography data

The structure of Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor, PDB code: 3s1y was solved by G.Scapin, J.Lu, P.M.D.Fitzgerald, N.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.40
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 43.253, 69.696, 101.667, 90.00, 90.00, 90.00
R / Rfree (%) 18.1 / 20.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor (pdb code 3s1y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor, PDB code: 3s1y:

Chlorine binding site 1 out of 1 in 3s1y

Go back to Chlorine Binding Sites List in 3s1y
Chlorine binding site 1 out of 1 in the Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Amp-C Beta-Lactamase (Pseudomonas Aeruginosa) in Complex with A Beta- Lactamase Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl399

b:19.1
occ:1.00
 O A:HOH1032 2.9 10.8 1.0
N A:PHE147 3.3 11.6 1.0
ND2 A:ASN179 3.4 11.2 1.0
CB A:ASN179 3.4 9.2 1.0
CA A:GLN146 3.6 11.8 1.0
O A:HOH1116 3.6 21.7 1.0
CD2 A:PHE147 3.7 10.0 1.0
O A:HOH1235 3.7 52.6 1.0
CB A:GLN146 3.7 12.4 1.0
CE2 A:TYR249 3.7 9.2 1.0
CG A:ASN179 3.9 10.4 1.0
C A:GLN146 3.9 11.5 1.0
CG A:GLN146 4.1 14.5 1.0
CB A:PHE147 4.2 11.6 1.0
C24 A:S1Y398 4.3 10.7 1.0
CA A:PHE147 4.3 11.7 1.0
CD A:PRO180 4.4 8.5 1.0
O A:PRO243 4.4 6.7 1.0
CG A:PHE147 4.4 10.3 1.0
C25 A:S1Y398 4.5 10.4 1.0
CD2 A:TYR249 4.5 9.6 1.0
OH A:TYR249 4.5 9.8 1.0
CZ A:TYR249 4.6 9.2 1.0
CE2 A:PHE147 4.6 9.8 1.0
O A:LEU145 4.7 10.5 1.0
CA A:ASN179 4.8 9.0 1.0
O A:PHE147 4.8 12.4 1.0
N A:GLN146 4.9 11.1 1.0
N A:PRO180 4.9 8.6 1.0

Reference:

H.Chen, T.A.Blizzard, S.Kim, J.Wu, K.Young, Y.W.Park, A.M.Ogawa, S.Raghoobar, R.E.Painter, D.Wisniewski, N.Hairston, P.Fitzgerald, N.Sharma, G.Scapin, J.Lu, J.Hermes, M.L.Hammond. Side Chain Sar of Bicyclic Beta-Lactamase Inhibitors (Blis). 2. N-Alkylated and Open Chain Analogs of Mk-8712 Bioorg.Med.Chem.Lett. V. 21 4267 2011.
ISSN: ISSN 0960-894X
PubMed: 21676616
DOI: 10.1016/J.BMCL.2011.05.065
Page generated: Fri Jul 11 10:04:47 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy