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Atomistry » Chlorine » PDB 3t52-3th3 » 3t8m | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3t52-3th3 » 3t8m » |
Chlorine in PDB 3t8m: Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta IsoformEnzymatic activity of Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform
All present enzymatic activity of Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform:
2.7.1.153; Protein crystallography data
The structure of Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform, PDB code: 3t8m
was solved by
J.M.Murray,
C.Wiesmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform
(pdb code 3t8m). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform, PDB code: 3t8m: Chlorine binding site 1 out of 1 in 3t8mGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform
![]() Mono view ![]() Stereo pair view
Reference:
T.Heffron,
B.Wei,
A.G.Olivero,
S.T.Staben,
V.Tsui,
S.Do,
J.Dotson,
A.Folkes,
A.Goldsmith,
R.Goldsmith,
J.Gunzner,
J.Lesnick,
C.Lewis,
S.Mathieu,
J.Nonomiya,
D.P.Sutherlin,
N.C.Wan,
S.Wang,
C.Weismann,
B.Zhu.
Rational Design of PI3K-Alpha Inhibitors That Exhibit Selectivity Over the PI3K-Beta Isoform To Be Published.
Page generated: Sun Jul 21 05:03:05 2024
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