Atomistry » Chlorine » PDB 3wav-3wnr » 3wf3
Atomistry »
  Chlorine »
    PDB 3wav-3wnr »
      3wf3 »

Chlorine in PDB 3wf3: Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose

Enzymatic activity of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose

All present enzymatic activity of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose:
3.2.1.23;

Protein crystallography data

The structure of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose, PDB code: 3wf3 was solved by H.Suzuki, U.Ohto, T.Shimizu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.30 / 2.15
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 94.960, 115.888, 140.284, 90.00, 92.23, 90.00
R / Rfree (%) 19.6 / 24.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose (pdb code 3wf3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose, PDB code: 3wf3:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 3wf3

Go back to Chlorine Binding Sites List in 3wf3
Chlorine binding site 1 out of 4 in the Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl706

b:21.4
occ:1.00
OG A:SER54 3.1 23.9 1.0
NE2 A:HIS56 3.1 20.4 1.0
NH2 A:ARG121 3.1 16.2 1.0
NE A:ARG121 3.3 17.2 1.0
CZ A:ARG121 3.6 17.7 1.0
CD2 A:HIS56 3.7 22.0 1.0
CG A:GLN81 3.8 25.4 1.0
O A:GLN81 3.8 22.0 1.0
CB A:SER54 3.8 21.8 1.0
CA A:THR82 3.8 20.2 1.0
C A:GLN81 3.9 21.9 1.0
NE2 A:GLN81 3.9 21.9 1.0
CD2 A:TYR83 3.9 20.4 1.0
C A:THR82 3.9 22.3 1.0
N A:THR82 4.0 20.6 1.0
CE2 A:TYR83 4.0 18.6 1.0
CE2 A:TYR306 4.1 20.3 1.0
N A:TYR83 4.1 20.7 1.0
CG A:TYR83 4.2 20.1 1.0
CD2 A:TYR306 4.2 19.3 1.0
CE1 A:HIS56 4.3 21.4 1.0
CB A:GLN81 4.3 24.3 1.0
O A:THR82 4.3 22.2 1.0
CD A:GLN81 4.3 24.3 1.0
CZ A:TYR83 4.5 19.9 1.0
CD A:ARG121 4.5 17.6 1.0
CA A:SER54 4.6 20.6 1.0
CD1 A:TYR83 4.6 20.8 1.0
CA A:GLN81 4.7 23.1 1.0
CE1 A:TYR83 4.8 20.9 1.0
CB A:TYR83 4.8 21.4 1.0
CG A:ARG121 4.9 17.7 1.0
CA A:TYR83 4.9 20.5 1.0

Chlorine binding site 2 out of 4 in 3wf3

Go back to Chlorine Binding Sites List in 3wf3
Chlorine binding site 2 out of 4 in the Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl705

b:20.2
occ:1.00
OG B:SER54 2.9 20.5 1.0
NH2 B:ARG121 3.2 19.5 1.0
NE2 B:HIS56 3.2 22.2 1.0
NE B:ARG121 3.3 19.8 1.0
CZ B:ARG121 3.6 20.1 1.0
CB B:SER54 3.7 20.4 1.0
CD2 B:HIS56 3.8 21.9 1.0
CG B:GLN81 3.9 22.4 1.0
O B:GLN81 3.9 20.5 1.0
NE2 B:GLN81 3.9 21.8 1.0
CA B:THR82 3.9 21.2 1.0
C B:GLN81 4.0 21.4 1.0
N B:THR82 4.0 22.8 1.0
C B:THR82 4.0 21.9 1.0
CE2 B:TYR306 4.1 17.6 1.0
CD2 B:TYR83 4.1 17.8 1.0
CD2 B:TYR306 4.2 18.9 1.0
N B:TYR83 4.2 17.4 1.0
CE2 B:TYR83 4.2 18.5 1.0
CG B:TYR83 4.3 16.8 1.0
CB B:GLN81 4.3 22.0 1.0
CE1 B:HIS56 4.4 21.6 1.0
CD B:GLN81 4.4 23.3 1.0
O B:THR82 4.5 23.3 1.0
CA B:SER54 4.5 20.4 1.0
CD B:ARG121 4.5 21.9 1.0
CZ B:TYR83 4.6 19.5 1.0
CD1 B:TYR83 4.6 16.8 1.0
CE1 B:TYR83 4.8 17.0 1.0
CG B:ARG121 4.8 19.4 1.0
CA B:GLN81 4.8 21.9 1.0
CB B:TYR83 4.9 16.4 1.0
NH1 B:ARG121 5.0 20.9 1.0
ND2 B:ASN304 5.0 24.6 1.0

Chlorine binding site 3 out of 4 in 3wf3

Go back to Chlorine Binding Sites List in 3wf3
Chlorine binding site 3 out of 4 in the Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl705

b:21.2
occ:1.00
OG C:SER54 2.9 20.4 1.0
NH2 C:ARG121 3.1 24.6 1.0
NE2 C:HIS56 3.2 17.8 1.0
NE C:ARG121 3.3 23.9 1.0
CZ C:ARG121 3.6 25.1 1.0
CB C:SER54 3.7 20.5 1.0
NE2 C:GLN81 3.7 18.4 1.0
O C:GLN81 3.7 25.0 1.0
CG C:GLN81 3.7 18.1 1.0
CA C:THR82 3.7 17.9 1.0
N C:THR82 3.8 18.4 1.0
C C:GLN81 3.8 18.9 1.0
CD2 C:HIS56 3.8 17.2 1.0
C C:THR82 3.9 19.0 1.0
CD2 C:TYR83 4.1 17.6 1.0
N C:TYR83 4.1 17.9 1.0
CB C:GLN81 4.1 18.3 1.0
CE2 C:TYR83 4.2 17.0 1.0
CE2 C:TYR306 4.2 21.7 1.0
CD C:GLN81 4.3 17.1 1.0
CG C:TYR83 4.3 17.6 1.0
CD2 C:TYR306 4.3 23.8 1.0
CE1 C:HIS56 4.4 16.7 1.0
O C:THR82 4.4 23.0 1.0
CA C:SER54 4.4 19.5 1.0
CZ C:TYR83 4.5 18.7 1.0
CD C:ARG121 4.5 23.2 1.0
CA C:GLN81 4.6 18.4 1.0
CD1 C:TYR83 4.6 18.4 1.0
CE1 C:TYR83 4.7 19.4 1.0
CG C:ARG121 4.7 23.3 1.0
ND2 C:ASN304 4.9 19.2 1.0
NH1 C:ARG121 5.0 25.7 1.0
CB C:TYR83 5.0 17.9 1.0

Chlorine binding site 4 out of 4 in 3wf3

Go back to Chlorine Binding Sites List in 3wf3
Chlorine binding site 4 out of 4 in the Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Human Beta-Galactosidase Mutant I51T in Complex with Galactose within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl705

b:20.5
occ:1.00
OG D:SER54 2.9 20.8 1.0
NE2 D:HIS56 3.1 18.5 1.0
NH2 D:ARG121 3.2 22.7 1.0
NE D:ARG121 3.4 23.1 1.0
O D:GLN81 3.6 20.2 1.0
CG D:GLN81 3.7 20.5 1.0
CZ D:ARG121 3.7 24.2 1.0
CB D:SER54 3.7 18.8 1.0
CD2 D:HIS56 3.8 17.5 1.0
NE2 D:GLN81 3.9 20.6 1.0
C D:GLN81 3.9 19.4 1.0
CA D:THR82 4.0 20.0 1.0
C D:THR82 4.0 20.6 1.0
CE2 D:TYR306 4.1 18.4 1.0
CD2 D:TYR83 4.1 19.2 1.0
N D:TYR83 4.1 20.1 1.0
N D:THR82 4.1 20.5 1.0
CD2 D:TYR306 4.2 20.2 1.0
CB D:GLN81 4.2 19.9 1.0
CE2 D:TYR83 4.2 19.3 1.0
CE1 D:HIS56 4.3 19.8 1.0
CD D:GLN81 4.3 22.2 1.0
O D:THR82 4.4 22.5 1.0
CG D:TYR83 4.4 18.3 1.0
CA D:SER54 4.4 17.7 1.0
CD D:ARG121 4.6 23.2 1.0
CZ D:TYR83 4.6 17.4 1.0
CD1 D:TYR83 4.7 17.4 1.0
CA D:GLN81 4.8 19.0 1.0
CE1 D:TYR83 4.8 18.3 1.0
CG D:ARG121 4.9 22.4 1.0
ND2 D:ASN304 4.9 21.2 1.0
CB D:TYR83 5.0 19.4 1.0

Reference:

H.Suzuki, U.Ohto, K.Higaki, T.Mena-Barragan, M.Aguilar-Moncayo, C.Ortiz Mellet, E.Nanba, J.M.Garcia Fernandez, Y.Suzuki, T.Shimizu. Structural Basis of Pharmacological Chaperoning For Human Beta-Galactosidase To Be Published.
Page generated: Fri Jul 11 11:58:02 2025

Last articles

Na in 2JBW
Na in 2JC4
Na in 2JBY
Na in 2JBA
Na in 2J9Y
Na in 2J9Z
Na in 2J9N
Na in 2J80
Na in 2J9E
Na in 2J5W
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy